Effectiveness of a three-month yoga protocol on glycemic control in type 2 diabetes mellitus: a systematic review and meta-analysis of randomized controlled trials.
A Vijay, G Sathiyavathi, S Suganthi, L Nivethitha, N Manavalan, A Mooventhan
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引用次数: 0
Abstract
Background: Type 2 diabetes mellitus (T2DM) is a major global health challenge, characterized by insulin resistance, progressive β-cell dysfunction, and persistent hyperglycemia. Yoga is a mind-body practice that has been studied as a potential complementary therapy for T2DM. However, no systematic review has specifically synthesized evidence on the effects of a three-month yoga intervention on glycemic control.
Methods: A systematic review and meta-analysis of randomized controlled trials (RCTs) was conducted in accordance with PRISMA guidelines (PROSPERO: CRD42024599832). Three electronic databases (PubMed, Science Direct, Cochrane Library) were searched from inception to October 2024. Eligible studies included participants with T2DM who had undergone yoga for three months. The primary outcome was glycated hemoglobin (HbA1c), secondary outcomes were fasting blood glucose (FBG) and postprandial blood glucose (PPBG).
Results: Fourteen RCTs comprising 1876 participants with T2DM met the eligibility criteria. Pooled analysis showed a significant reduction in HbA1c (Mean difference [MD] = - 0.55; 95% Confidence interval [CI]: - 1.02 to - 0.08; I² = 97%), FBG (MD = - 24.72 mg/dL; 95% CI: - 34.10 to - 15.34; I² = 80%), and PPBG (MD = - 26.01 mg/dL; 95% CI: - 40.91 to - 11.12; I² = 51%) after three months of yoga. Most trials had a high overall risk of bias.
Conclusion: A three-month yoga practice significantly reduces HbA1c, FBG, and PPBG in participants with T2DM without adverse effects, supporting its role as a safe, low-cost adjunct to standard care. However, high heterogeneity restricts certainty. High-quality, multicenter RCTs with standardized yoga protocols are warranted to confirm these findings.
期刊介绍：
Journal of Diabetes & Metabolic Disorders is a peer reviewed journal which publishes original clinical and translational articles and reviews in the field of endocrinology and provides a forum of debate of the highest quality on these issues. Topics of interest include, but are not limited to, diabetes, lipid disorders, metabolic disorders, osteoporosis, interdisciplinary practices in endocrinology, cardiovascular and metabolic risk, aging research, obesity, traditional medicine, pychosomatic research, behavioral medicine, ethics and evidence-based practices.As of Jan 2018 the journal is published by Springer as a hybrid journal with no article processing charges. All articles published before 2018 are available free of charge on springerlink.Unofficial 2017 2-year Impact Factor: 1.816.
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