Enhancing Chemotherapy Adherence in Cancer Management: A Quasi-Experimental Trial of a Smartphone Application.

IF 2.2 4区医学 Q3 ONCOLOGY

Cancer Investigation Pub Date : 2026-02-01 Epub Date: 2025-12-02 DOI:10.1080/07357907.2025.2596851

Hari Prakash, Sunil Kumar D, Kiran Pk, Vanishri Arun, Deepika Yadav, Arun Gopi

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引用次数: 0

Abstract

Background: Suboptimal adherence to chemotherapy regimens remains a significant challenge in cancer management, adversely impacting treatment outcomes and quality of life. This study aimed to develop and evaluate a user-centric mobile app intervention to promote adherence and enhance quality of life among cancer patients undergoing chemotherapy.

Methodology: A quasi-experimental trial was conducted with 60 cancer patients undergoing chemotherapy, randomly assigned to an experimental group (n = 30) using the mobile app or a control group (n = 30) receiving standard care. Medication adherence was assessed using the Medication Adherence Measure Scale (MAMS), and quality of life was evaluated using the EORTC QLQ-C30 questionnaire at baseline and after one month of intervention.

Results: At baseline, no significant differences between the groups were observed in adherence levels or quality of life measures. However, after one month, the experimental group demonstrated a significant improvement in medication adherence (mean MAMS score increase from 3.03 to 4.88, p = 0.012) and better scores in physical, role, emotional, and cognitive functioning domains compared to the control group (p < 0.05).

Conclusion: The user-centric mobile app intervention showed potential efficacy in improving adherence to chemotherapy regimens and enhancing the specific quality of life domains among cancer patients.

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在癌症管理中增强化疗依从性：智能手机应用程序的准实验试验。

背景：化疗方案的次优依从性仍然是癌症管理中的一个重大挑战，对治疗结果和生活质量产生不利影响。本研究旨在开发和评估以用户为中心的移动应用程序干预，以促进接受化疗的癌症患者的依从性和提高生活质量。方法：采用准实验方法对60例正在接受化疗的癌症患者进行试验，随机分为使用移动应用程序的实验组（n = 30）和接受标准治疗的对照组（n = 30）。采用药物依从性量表（MAMS）评估患者的药物依从性，在基线和干预1个月后采用EORTC QLQ-C30问卷评估患者的生活质量。结果：在基线时，两组在依从性水平或生活质量测量方面没有观察到显著差异。然而，一个月后，实验组在药物依从性方面表现出显著改善（平均MAMS评分从3.03增加到4.88,p = 0.012），在身体、角色、情感和认知功能领域的得分较对照组更好(p结论：以用户为中心的移动应用干预在提高癌症患者对化疗方案的依从性和提高特定生活质量领域方面显示出潜在的疗效。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Cancer Investigation 医学-肿瘤学

CiteScore

3.80

自引率

4.20%

发文量

审稿时长

8.5 months

期刊介绍： Cancer Investigation is one of the most highly regarded and recognized journals in the field of basic and clinical oncology. It is designed to give physicians a comprehensive resource on the current state of progress in the cancer field as well as a broad background of reliable information necessary for effective decision making. In addition to presenting original papers of fundamental significance, it also publishes reviews, essays, specialized presentations of controversies, considerations of new technologies and their applications to specific laboratory problems, discussions of public issues, miniseries on major topics, new and experimental drugs and therapies, and an innovative letters to the editor section. One of the unique features of the journal is its departmentalized editorial sections reporting on more than 30 subject categories covering the broad spectrum of specialized areas that together comprise the field of oncology. Edited by leading physicians and research scientists, these sections make Cancer Investigation the prime resource for clinicians seeking to make sense of the sometimes-overwhelming amount of information available throughout the field. In addition to its peer-reviewed clinical research, the journal also features translational studies that bridge the gap between the laboratory and the clinic.