Association between Health Eating Index-2015 and prostate-specific antigen levels: a cross-sectional study of NHANES 2001-2004.

IF 4.5 4区医学 Q2 FOOD SCIENCE & TECHNOLOGY

Food & Nutrition Research Pub Date : 2025-09-25 eCollection Date: 2025-01-01 DOI:10.29219/fnr.v69.12639

Xingpeng Di, Jie Zhang, Liyuan Xiang, Xin Wei, Banghua Liao

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引用次数: 0

Abstract

Objectives: Prostate cancer is the most common carcinoma among men worldwide. To elaborate the effect of dietary quality on prostate-specific antigen (PSA), we investigated the association between Health Eating Index-2015 (HEI-2015) and PSA concentration from National Health and Nutrition Examination Survey.

Methods: This cross-sectional analysis of men aged 40 years and older was enrolled from the year 2001-2004. Weighted multivariable logistic and linear regression models were employed to evaluate the association between the HEI-2015 and PSA level.

Results: A total of 1,467 males were enrolled in the study. The results demonstrated that a higher HEI-2015 score was associated with a lower PSA level in the fully-adjusted model (β = -0.388, 95% Confidence interval (CI) = -0.746 to -0.030, P = 0.030). Specifically, the consumption of seafood and plant proteins group was found to have an inverse correlation with PSA levels (β = -0.049, 95% CI = -0.088 to -0.009, P = 0.020).

Conclusion: Our findings indicate that a higher HEI-2015 score is associated with a reduced risk of PSA among adult men aged 40-55 years in the United States. Furthermore, race, body mass index (BMI), and alcohol drinking may be modifiers of the relationship.

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健康饮食指数-2015与前列腺特异性抗原水平之间的关系：NHANES 2001-2004的横断面研究

目的：前列腺癌是世界范围内男性最常见的癌症。为了阐明膳食质量对前列腺特异性抗原（PSA）的影响，我们调查了国家健康与营养检查调查中健康饮食指数-2015 （HEI-2015）与PSA浓度的关系。方法：对2001-2004年40岁及以上的男性进行横断面分析。采用加权多变量logistic和线性回归模型评估HEI-2015与PSA水平的相关性。结果：共有1467名男性参与了这项研究。结果显示，在完全调整模型中，HEI-2015评分越高，PSA水平越低（β = -0.388, 95%置信区间(CI) = -0.746 ~ -0.030, P = 0.030）。具体而言，食用海鲜和植物蛋白组与PSA水平呈负相关（β = -0.049, 95% CI = -0.088至-0.009,P = 0.020）。结论：我们的研究结果表明，在美国40-55岁的成年男性中，较高的HEI-2015评分与PSA风险降低相关。此外，种族、身体质量指数（BMI）和饮酒可能是这种关系的调节因素。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Food & Nutrition Research FOOD SCIENCE & TECHNOLOGY-NUTRITION & DIETETICS

CiteScore

5.20

自引率

9.10%

发文量

审稿时长

14 weeks

期刊介绍： Food & Nutrition Research is a peer-reviewed journal that presents the latest scientific research in various fields focusing on human nutrition. The journal publishes both quantitative and qualitative research papers. Through an Open Access publishing model, Food & Nutrition Research opens an important forum for researchers from academic and private arenas to exchange the latest results from research on human nutrition in a broad sense, both original papers and reviews, including: * Associations and effects of foods and nutrients on health * Dietary patterns and health * Molecular nutrition * Health claims on foods * Nutrition and cognitive functions * Nutritional effects of food composition and processing * Nutrition in developing countries * Animal and in vitro models with clear relevance for human nutrition * Nutrition and the Environment * Food and Nutrition Education * Nutrition and Economics Research papers on food chemistry (focus on chemical composition and analysis of foods) are generally not considered eligible, unless the results have a clear impact on human nutrition. The journal focuses on the different aspects of nutrition for people involved in nutrition research such as Dentists, Dieticians, Medical doctors, Nutritionists, Teachers, Journalists and Manufacturers in the food and pharmaceutical industries.