The role of sequential sexual acts on Neisseria gonorrhoea transmissions between anatomical sites in men who have sex with men: a mathematical modelling study.

IF 2 4区医学 Q3 INFECTIOUS DISEASES

Sexual health Pub Date : 2025-12-23 DOI:10.1071/SH25128

Mengjie Wang, Hao Lai, Christopher K Fairley, Nyi Nyi Soe, Phyu Mon Latt, Mingwang Shen, Shu Su, Rui Zhao, Leilei Zhang, Yi Zhou, Pingyu Zhou, Zengbin Li, Lei Zhang

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引用次数: 0

Abstract

Background: To investigate which sequential sexual acts involving different anatomical sites had the most affect on the transmission of gonorrhoea in men who have sex with men (MSM).

Methods: A mathematical model was constructed to simulate gonorrhoea transmission between the sequential sexual acts involving the oropharynx, urethra and anorectum. We simulated 1,000,000 sexual episodes using data of the sexual behaviours of a recent cohort of MSM, and identified which acts contributed most to transmission events. The potential impact of condom use on gonorrhoea transmissions was also evaluated.

Results: We used data on 2286 sex episodes that involved 294 different sexual patterns from 312 MSM followed for 12 weeks. Of the 1,000,000 model-simulated sexual episodes, 83.50% of 2468 transmissions occurred in sexual episodes that involved the oropharynx, with kissing accounting for the majority (68.85%). The three most frequent individual sexual behavioural patterns were 'kissing only', 'kissing-receptive oral sex-insertive anal sex' and 'kissing-insertive oral sex-receptive anal sex'. These contributed to 341, 209 and 166 transmissions, respectively. The increasing coverage of condoms (80%) could potentially reduce gonorrhoea transmissions by 8.49% to 2259 cases/million sex episodes.

Conclusions: Oropharynx-related sexual acts contribute to most gonorrhoea transmission. Condom use has a limited impact on gonorrhoea transmission.

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连续性行为对淋病奈瑟菌在男男性性交者解剖部位之间传播的作用：一项数学模型研究。

目的：探讨哪些涉及不同解剖部位的连续性行为对男男性行为（MSM）淋病传播的影响最大。方法：建立数学模型，模拟淋病在口咽、尿道、肛肠连续性行为中的传播。我们利用最近一批男男性接触者的性行为数据模拟了1,000,000次性行为，并确定了哪些行为对传播事件贡献最大。还评估了使用避孕套对淋病传播的潜在影响。结果：我们使用了3286次性行为的数据，涉及294种不同的性模式，来自312名MSM，随访12周。在1,000,000次模型模拟的性行为中，2,468次传播中有83.50%发生在涉及口咽部的性行为中，其中接吻占大多数（68.85%）。最常见的三种个体性行为模式是“只接吻”、“接吻-接受口交-插入肛交”和“接吻-插入口交-接受肛交”。它们分别造成了341、209和166次传播。增加避孕套的覆盖率（80%）可能会使淋病传播减少8.49%，降至2259例/百万次性行为。结论：与口咽有关的性行为是淋病传播的主要途径。使用避孕套对淋病传播的影响有限。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Sexual health 医学-传染病学

CiteScore

2.30

自引率

12.50%

发文量

121

审稿时长

6-12 weeks

期刊介绍： Sexual Health publishes original and significant contributions to the fields of sexual health including HIV/AIDS, Sexually transmissible infections, issues of sexuality and relevant areas of reproductive health. This journal is directed towards those working in sexual health as clinicians, public health practitioners, researchers in behavioural, clinical, laboratory, public health or social, sciences. The journal publishes peer reviewed original research, editorials, review articles, topical debates, case reports and critical correspondence. Officially sponsored by: The Australasian Chapter of Sexual Health Medicine of RACP Sexual Health Society of Queensland Sexual Health is the official journal of the International Union against Sexually Transmitted Infections (IUSTI), Asia-Pacific, and the Asia-Oceania Federation of Sexology.