Bilateral endogenous fungal endophthalmitis following elective surgical abortion: a single center case series.

IF 2 Q1 OPHTHALMOLOGY
Viet Q Chau, Jesse D Sengillo, Flavius A Beca, Julia L Hudson, Thomas A Albini, Harry W Flynn
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Abstract

Background: To describe the clinical features and management of three cases of bilateral endogenous fungal endophthalmitis following elective surgical abortion performed at the same outpatient surgical center.

Methods: Case series.

Observations: Three immunocompetent women presented with vision loss days to weeks following elective surgical abortions performed at a single outpatient clinic. Initial visual acuities ranged from 20/20 to 20/300. Fundoscopic examination revealed multiple white round chorioretinal lesions with vitreous infiltration bilaterally in all three patients. Vitreous tap samples were obtained for culture and broad-spectrum intravitreal antimicrobials were administered. Despite negative cultures and systemic workup, the clinical presentation was consistent with fungal endophthalmitis. All patients received systemic and intravitreal antifungal therapy, leading to gradual resolution of lesions and improvement of visual acuity to 20/25 or better in all eyes.

Conclusions: This cases series represents the first reported cluster of endogenous fungal endophthalmitis following surgical abortion. Prompt recognition and treatment with intravitreal and systemic antifungals can result in favorable outcomes. The findings highlight the importance of stringent sterilization protocols in outpatient surgical settings and the need for heighted clinical suspicion in similar presentations.

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选择性手术流产后双侧内源性真菌性眼内炎:单中心病例系列。
背景:描述在同一门诊外科中心择期手术流产后发生的3例双侧内源性真菌性眼内炎的临床特点和处理。方法:病例系列。观察:三名免疫功能正常的妇女在选择性手术流产后几天到几周内出现视力丧失。初始视力在20/20到20/300之间。眼底镜检查均发现双侧多发性白色圆形脉络膜病变伴玻璃体浸润。获得玻璃体水龙头样本进行培养,并给予广谱玻璃体内抗菌剂。尽管阴性培养和全身检查,临床表现符合真菌性眼内炎。所有患者均接受了全身和玻璃体内抗真菌治疗,病变逐渐消退,全眼视力改善至20/25或更好。结论:本病例系列是首次报道的手术流产后内源性真菌性眼内炎集群。及时识别和治疗玻璃体内和全身抗真菌药物可导致良好的结果。研究结果强调了在门诊手术环境中严格消毒方案的重要性,以及在类似表现中高度临床怀疑的必要性。
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来源期刊
CiteScore
3.80
自引率
3.40%
发文量
39
审稿时长
13 weeks
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