Burden of Musculoskeletal and Headache Disorders in Asian Countries, 1990-2021: A Cross-Sectional Analysis of the Global Burden of Disease Study 2021.

IF 1.9 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Youngoh Bae, Suho Jang, Woonyoung Jeong, Jisoo Tak, Seung Won Lee
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Abstract

Background: Comprehensive and updated data on the prevalence, incidence, mortality, and disability rates of musculoskeletal (MSK) and headache disorders in Asia are scarce. We aimed to analyze the trends in incidence, prevalence, mortality, and disability-adjusted life years (DALYs) related to these disorders from 1990 to 2021.

Methods: We assessed the burden of MSK and headache disorders across Asia utilizing data from the Global Burden of Disease study. We evaluated the trends in DALYs, mortality, incidence, and prevalence and their changes over time. Correlations with the sociodemographic index were examined to determine potential influencing factors.

Results: In 2021, MSK and headache disorders accounted for 120 million DALYs (95% uncertainty interval: 72.5-182.3 million), reflecting a 94% increase since 1990. Furthermore, mortality increased by 138% over the same period. Lower back pain was the leading contributor to DALYs (36.9 million), followed by migraine (25.4 million) and knee osteoarthritis (7.4 million). From 1990 to 2021, DALYs due to osteoarthritis and gout increased by 15% and 170%, respectively. DALYs due to rheumatoid arthritis (RA) remained stable, although RA-related mortality increased by 117%. Age-standardized rates exhibited minimal variation, with the highest burden observed in individuals aged 50-54 years and a higher prevalence among females.

Conclusion: MSK and headache disorders were leading causes of disability in Asia, with significant increments in both DALYs and mortality over the past three decades. These trends underscore the urgent need for targeted prevention and management strategies, particularly for high-burden conditions like lower back pain, migraine, and osteoarthritis.

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1990-2021年亚洲国家肌肉骨骼和头痛疾病负担:2021年全球疾病负担研究的横断面分析
背景:关于亚洲肌肉骨骼(MSK)和头痛疾病的患病率、发病率、死亡率和致残率的全面和最新数据很少。我们的目的是分析1990年至2021年与这些疾病相关的发病率、患病率、死亡率和残疾调整生命年(DALYs)的趋势。方法:我们利用全球疾病负担研究的数据评估了亚洲地区MSK和头痛疾病的负担。我们评估了DALYs、死亡率、发病率和患病率的趋势及其随时间的变化。研究了与社会人口指数的相关性,以确定潜在的影响因素。结果:2021年,MSK和头痛疾病占1.2亿DALYs(95%不确定区间:7250 - 1.823亿),自1990年以来增加了94%。此外,同期死亡率增加了138%。腰痛是DALYs的主要贡献者(3690万),其次是偏头痛(2540万)和膝关节骨关节炎(740万)。从1990年到2021年,骨关节炎和痛风导致的DALYs分别增加了15%和170%。类风湿性关节炎(RA)导致的DALYs保持稳定,尽管RA相关死亡率增加了117%。年龄标准化率表现出最小的变化,在50-54岁的个体中观察到的负担最高,女性患病率更高。结论:在亚洲,MSK和头痛疾病是致残的主要原因,在过去的30年里,DALYs和死亡率都有显著的增加。这些趋势强调迫切需要有针对性的预防和管理策略,特别是对于腰痛、偏头痛和骨关节炎等高负担疾病。
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来源期刊
Iranian Journal of Public Health
Iranian Journal of Public Health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-
CiteScore
2.20
自引率
7.10%
发文量
300
审稿时长
3-8 weeks
期刊介绍: Iranian Journal of Public Health has been continuously published since 1971, as the only Journal in all health domains, with wide distribution (including WHO in Geneva and Cairo) in two languages (English and Persian). From 2001 issue, the Journal is published only in English language. During the last 41 years more than 2000 scientific research papers, results of health activities, surveys and services, have been published in this Journal. To meet the increasing demand of respected researchers, as of January 2012, the Journal is published monthly. I wish this will assist to promote the level of global knowledge. The main topics that the Journal would welcome are: Bioethics, Disaster and Health, Entomology, Epidemiology, Health and Environment, Health Economics, Health Services, Immunology, Medical Genetics, Mental Health, Microbiology, Nutrition and Food Safety, Occupational Health, Oral Health. We would be very delighted to receive your Original papers, Review Articles, Short communications, Case reports and Scientific Letters to the Editor on the above men­tioned research areas.
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