Multiple Case Studies on the Effects of Aroma Massage for Pain Relief and Quality of Life in Parkinson's Disease Patients.

Q3 Medicine

Tokai Journal of Experimental and Clinical Medicine Pub Date : 2025-12-20

Izumi Aoyama, Tatsuya Nogami, Eiichiro Nagata

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引用次数: 0

Abstract

Objective: This study investigated the effects of Aromatherapy Massage on chronic pain and quality of life (QOL) in four patients with Parkinson's disease (PD) whose pain was unresponsive to medication.

Methods: A three-arm crossover trial was conducted, consisting of Inhalation (I), Massage (M), and Aromatherapy Massage (AM), each over three weeks. Pain was assessed using the Visual Analog Scale (VAS) and King's PD Pain Scale (KPPS). Plasma dopamine and β-endorphin levels and electroencephalography (EEG) were used as objective indicators. QOL was measured using the PDQ-39. Data were analyzed with linear mixed models (p < 0.05).

Results: Only AM significantly increased plasma dopamine. Both M and AM elevated β-endorphin levels and reduced VAS scores during and after intervention. KPPS scores improved following AM. EEG showed the highest peak alpha frequency during AM. PDQ-39 scores improved by 3.75 points after AM.

Conclusion: Aromatherapy massage may offer effective multisensory stimulation for alleviating chronic pain and enhancing QOL in PD patients. It may serve as a useful complementary strategy in pain management.

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芳香按摩对帕金森病患者疼痛缓解和生活质量影响的多例研究

目的：探讨芳香按摩对4例疼痛对药物无反应的帕金森病（PD）患者慢性疼痛及生活质量的影响。方法：进行了三组交叉试验，包括吸入(I)，按摩(M)和芳香疗法按摩（AM），每组为期三周。采用视觉模拟量表（VAS）和King’s PD疼痛量表（KPPS）评估疼痛。以血浆多巴胺、β-内啡肽水平和脑电图（EEG）作为客观指标。使用PDQ-39测量生活质量。数据采用线性混合模型分析（p < 0.05）。结果：仅AM可显著增加血浆多巴胺。在干预期间和干预后，M和AM均升高β-内啡肽水平，降低VAS评分。AM后KPPS评分有所提高。脑电图显示AM时段α频率峰值最高。PDQ-39得分在AM后提高了3.75分。结论：芳香按摩可提供有效的多感官刺激，减轻PD患者的慢性疼痛，提高患者的生活质量。它可以作为一个有用的补充策略，在疼痛管理。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Tokai Journal of Experimental and Clinical Medicine Medicine-Medicine (all)

CiteScore

1.10

自引率

0.00%

发文量

期刊介绍： The Tokai Journal of Experimental and Clinical Medicine, also referred to as Tokai Journal, is an official quarterly publication of the Tokai Medical Association. Tokai Journal publishes original articles that deal with issues of clinical, experimental, socioeconomic, cultural and/or historical importance to medical science and related fields. Manuscripts may be submitted as full-length Original Articles or Brief Communications. Tokai Journal also publishes reviews and symposium proceedings. Articles accepted for publication in Tokai Journal cannot be reproduced elsewhere without written permission from the Tokai Medical Association. In addition, Tokai Journal will not be held responsible for the opinions of the authors expressed in the published articles.