Liv Ilgner, Andreas Eckert, Sibylle C Roll, Marjan van den Akker, Andreas Reif, Martina Hahn
{"title":"[Focusing on psychotropic drug interactions - Development of an 11-Item tool to compare interaction databases for psychiatric practice].","authors":"Liv Ilgner, Andreas Eckert, Sibylle C Roll, Marjan van den Akker, Andreas Reif, Martina Hahn","doi":"10.1055/a-2695-6723","DOIUrl":null,"url":null,"abstract":"<p><p>The objective is the development and pilot testing of a evaluation system designed to facilitate the objective and systematic comparison of interaction databases, Especially in the psychiatric context.The study examined medication plans of 104 psychiatric patients. The medication was checked for interactions in twelve databases. A newly developed evaluation system with 11 criteria and a scoring system was used for evaluation.The number of interactions detected differs significantly between the databases. No database achieved the maximum number of points. Paid databases scored better on average (6.4±2,5 points) than free ones (1.5±2,4 points, p=0,009). The best results were achieved by ifap and PGXperts.Psychotropic substances have a high potential for interactions. Using multiple databases is recommended, combined with clinical experience and interdisciplinary collaboration.</p>","PeriodicalId":20711,"journal":{"name":"Psychiatrische Praxis","volume":"52 8","pages":"430-435"},"PeriodicalIF":0.9000,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Psychiatrische Praxis","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1055/a-2695-6723","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/11/12 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"PSYCHIATRY","Score":null,"Total":0}
引用次数: 0
Abstract
The objective is the development and pilot testing of a evaluation system designed to facilitate the objective and systematic comparison of interaction databases, Especially in the psychiatric context.The study examined medication plans of 104 psychiatric patients. The medication was checked for interactions in twelve databases. A newly developed evaluation system with 11 criteria and a scoring system was used for evaluation.The number of interactions detected differs significantly between the databases. No database achieved the maximum number of points. Paid databases scored better on average (6.4±2,5 points) than free ones (1.5±2,4 points, p=0,009). The best results were achieved by ifap and PGXperts.Psychotropic substances have a high potential for interactions. Using multiple databases is recommended, combined with clinical experience and interdisciplinary collaboration.
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