Two new macrocyclic cembrane diterpenoids from Boswellia seratta gum resin.

IF 1.6 3区医学 Q3 CHEMISTRY, APPLIED

Journal of Asian Natural Products Research Pub Date : 2026-08-01 Epub Date: 2025-11-13 DOI:10.1080/10286020.2025.2583447

Durgaprasad Metta, Raveendra Babu Kothapalli, Ramarao Paidi, Ramakrishna Singuru

引用次数: 0

Abstract

Two previously undescribed macrocyclic diterpenoids, cycloserratol (1) and isopapyrifuranol A (2) were isolated from the gum resin of Boswellia seratta. Compound 1 was confirmed as trihydroxy substituted 12-membered macrocyclic cembrane-type diterpenoid skeleton and 2 was a new 1,12-oxygen fused trihydroxy cembrane skeleton. The structures of these new metabolites were characterized by HRESIMS, 1D NMR and 2D NMR analysis.

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两个新的大环膜二萜类化合物的研究。

两个先前描述的大环二萜类化合物，环塞拉醇(1)和异吡喃醇A(2)从树胶树脂中分离得到。化合物1为三羟基取代的12元大环膜型二萜骨架，化合物2为新的1,12氧融合的三羟基膜骨架。这些新代谢物的结构通过HRESIMS、1D NMR和2D NMR分析进行了表征。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Asian Natural Products Research 医学-药学

CiteScore

3.20

自引率

5.90%

发文量

审稿时长

2.3 months

期刊介绍： The Journal of Asian Natural Products Research (JANPR) publishes chemical and pharmaceutical studies in the English language in the field of natural product research on Asian ethnic medicine. The journal publishes work from scientists in Asian countries, e.g. China, Japan, Korea and India, including contributions from other countries concerning natural products of Asia. The journal is chemistry-orientated. Major fields covered are: isolation and structural elucidation of natural constituents (including those for non-medical uses), synthesis and transformation (including biosynthesis and biotransformation) of natural products, pharmacognosy, and allied topics. Biological evaluation of crude extracts are acceptable only as supporting data for pure isolates with well-characterized structures. All published research articles in this journal have undergone rigorous peer review, based on initial editor screening and anonymized refereeing by at least two expert referees.