Effects of fine particulate matter air pollution on cardiovascular mortality in Dhaka, Bangladesh, from 2020 to 2024.

Abdullah Al Nayeem, Mahmuda Islam
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Abstract

Introduction: Although air pollution is a leading cause of mortality in Bangladesh, epidemiological studies remain limited and largely focus on exposure rather than health outcomes. Therefore, we investigated the effects of fine particulate matter (PM2.5) exposure on Cardiovascular Disease (CVD) mortality in Dhaka city.

Methods: We collected monthly CVD mortality records from four major government medical college hospitals in Dhaka city between 2020 and 2024. We obtained corresponding PM2.5 concentrations from the Department of Environment and meteorological data from NASA POWER project. We applied a Generalized Additive Model (GAM) with a quasi-Poisson distribution and incorporated lag structures to estimate the percentage change in CVD mortality per 10 µg/m³ increase in PM2.5 concentration.

Results: We found a total of 17,531 CVD deaths during the study period. A 10 µg/m³ increase in PM2.5 concentration was associated with a 3.1 % increase in CVD mortality at lag 0 (95 % CI: 1.1 % , 5.2 %). Furthermore, an estimated 16 % of total CVD deaths during the study period were attributable to PM2.5 exposure. Seasonal analysis showed that 28.7 % of CVD deaths in cold months were attributable to PM2.5, compared to only 7.15 % during the hot months. The exposure-response relationship was non-linear and showed a gradual increase in CVD mortality, indicating higher health risks at high levels of PM2.5.

Conclusion: Our study provides clear evidence that elevated PM2.5 concentrations significantly contribute to cardiovascular mortality in Dhaka city. Therefore, reducing PM2.5 through urgent and sustained policy action, targeted emission control, and improved monitoring could substantially lower CVD mortality and mitigate the growing health impacts of air pollution in urban Bangladesh.

2020年至2024年细颗粒物空气污染对孟加拉国达卡心血管死亡率的影响。
导言:虽然空气污染是孟加拉国死亡的主要原因,但流行病学研究仍然有限,而且主要侧重于接触而不是健康结果。因此,我们调查了细颗粒物(PM2.5)暴露对达卡市心血管疾病(CVD)死亡率的影响。方法:收集达卡市4所主要公立医学院医院2020 - 2024年每月CVD死亡率记录。我们从环境部和NASA POWER项目的气象数据中获得了相应的PM2.5浓度。我们采用准泊松分布的广义加性模型(GAM)并结合滞后结构来估计PM2.5浓度每增加10µg/m³心血管疾病死亡率的百分比变化。结果:我们发现在研究期间共有17531例心血管疾病死亡。PM2.5浓度每增加10µg/m³,滞后期心血管疾病死亡率增加3.1% (95% CI: 1.1%, 5.2%)。此外,在研究期间,估计有16%的心血管疾病死亡可归因于PM2.5暴露。季节性分析显示,寒冷月份28.7%的心血管疾病死亡可归因于PM2.5,而炎热月份仅为7.15%。暴露-反应关系呈非线性,心血管疾病死亡率呈逐渐上升趋势,表明PM2.5水平高时健康风险更高。结论:我们的研究提供了明确的证据,表明PM2.5浓度升高显著增加了达卡市心血管疾病死亡率。因此,通过紧急和持续的政策行动、有针对性的排放控制和改进监测来减少PM2.5,可以大幅降低心血管疾病死亡率,减轻孟加拉国城市空气污染对健康日益严重的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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