A Rare Case of Adult Rhabdomyoma in the Parapharyngeal Space: Diagnostic Challenges and Surgical Management.

IF 0.4 Q4 PATHOLOGY
Case Reports in Pathology Pub Date : 2025-10-31 eCollection Date: 2025-01-01 DOI:10.1155/crip/1626816
Alkmini Gatsounia, Pinelopi Bosgana, Gerasimos Danielides, Athanasios Vlachodimitropoulos, Hamida Kurabi, Spyridon Lygeros
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引用次数: 0

Abstract

Introduction: Adult rhabdomyoma (ARM) is an exceedingly rare benign neoplasm accounting for less than 2% of all striated muscle tumors. Originating from striated muscle cells, it primarily occurs in the head and neck region but is particularly rare in the parapharyngeal space.

Case presentation: We report a case of a 64-year-old male patient who presented with a 6-month history of progressive dysphagia and globus pharyngeus. CT and MRI scans revealed a well-defined multilobular mass in the right parapharyngeal space. Surgical excision was performed, and histopathological evaluation confirmed ARM. ARM diagnosis presents a challenge due to nonspecific clinical and radiological manifestations. Histopathological examination remains the gold standard for definitive diagnosis. Surgical excision is the treatment of choice, and close postoperative monitoring is crucial due to high recurrence rates.

Conclusion: This case highlights the diagnostic challenges and treatment modalities for ARM in a rare anatomical location. A multidisciplinary approach incorporating radiological, cytological, and histopathological evaluations is essential for accurate diagnosis and effective management.

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成人咽旁间隙横纹瘤1例:诊断挑战及手术处理。
成人横纹肌瘤(Adult rhabdomyoma, ARM)是一种极为罕见的良性肿瘤,占横纹肌肿瘤的不到2%。它起源于横纹肌细胞,主要发生在头颈部,但在咽旁间隙特别罕见。病例介绍:我们报告一例64岁男性患者,其表现为6个月进行性吞咽困难和咽球挛缩。CT和MRI扫描显示在右侧咽旁间隙有明确的多小叶肿块。手术切除,组织病理学检查证实为ARM。由于非特异性的临床和放射学表现,ARM的诊断提出了挑战。组织病理学检查仍然是确诊的金标准。手术切除是治疗的选择,密切的术后监测是至关重要的,因为高复发率。结论:该病例突出了在罕见解剖位置的ARM的诊断挑战和治疗方式。结合放射学、细胞学和组织病理学评估的多学科方法对于准确诊断和有效管理至关重要。
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