Global prevalence of stroke-associated pneumonia: a systematic review and meta-analysis of cross-sectional studies.

IF 2.3 4区医学 Q1 REHABILITATION

Topics in Stroke Rehabilitation Pub Date : 2026-07-01 Epub Date: 2025-11-06 DOI:10.1080/10749357.2025.2585118

Sogand Sarmadi, Neda Sanaie, Akbar Zare-Kaseb

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引用次数: 0

Abstract

Background: Neurological damage resulting from stroke can impair the respiratory system, leaving stroke patients susceptible to pulmonary complications, such as stroke-associated pneumonia (SAP). Due to the substantial mortality risk associated with SAP and its complications, we conducted a systematic review and meta-analysis to estimate the global prevalence of SAP.

Method: A comprehensive search of MEDLINE via PubMed, EMBASE, Scopus, and Web of Science was conducted from 1 January 2014 to 7 August 2024. The cross-sectional studies were selected. The primary study outcome was the prevalence of SAP. Subgroup analysis was implemented. The random-effects method was used to implement meta-analysis. The Joanna Briggs Institute tool for prevalence was used to assess risk of bias in the included studies.

Result: A comprehensive search of MEDLINE via PubMed, EMBASE, Scopus, and Web of Science was conducted from 1 January 2014 to 7 August 2024. The cross-sectional studies were selected. The primary study outcome was the prevalence of SAP. Subgroup analysis was implemented. The random-effects method was used to implement meta-analysis. The Joanna Briggs Institute tool for prevalence was used to assess risk of bias in the included studies. Result The present systematic review and meta-analysis integrated data from 24 studies, encompassing 4,272,805 participants. The prevalence of SAP was 18.3% (95% CI: 13.7-23.0). Results showed significant heterogeneity among studies regarding prevalence estimates (I2= 99.74%, p<0.001). Subgroup analysis by country revealed a substantial reduction in heterogeneity within one specific subgroup (I2=0.00, P=0.67). Utilizing Begg's and Egger's tests showed no statistically significant evidence (P = 0.9013 and P = 0.8398, respectively) of publication bias. The trim-and-fill analysis did not impute additional studies, implying that publication bias is unlikely. A leave-one-out sensitivity analysis revealed that excluding the study by Asgedom et al. resulted in the most significant change in the overall prevalence of SAP.

Conclusion: Our results emphasized the need to effectively identify and manage risk factors to reduce the likelihood of SAP.

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卒中相关肺炎的全球患病率：横断面研究的系统回顾和荟萃分析

背景：脑卒中引起的神经损伤可损害呼吸系统，使脑卒中患者容易发生肺部并发症，如脑卒中相关性肺炎（SAP）。由于与SAP及其并发症相关的大量死亡风险，我们进行了系统回顾和荟萃分析，以估计SAP的全球患病率。方法：从2014年1月1日至2024年8月7日，通过PubMed， EMBASE， Scopus和Web of Science对MEDLINE进行全面搜索。我们选择了横断面研究。主要研究结果是SAP的患病率。进行亚组分析。采用随机效应法进行meta分析。乔安娜布里格斯研究所的流行率工具被用来评估纳入研究的偏倚风险。结果：从2014年1月1日至2024年8月7日，通过PubMed、EMBASE、Scopus和Web of Science对MEDLINE进行了全面检索。我们选择了横断面研究。主要研究结果是SAP的患病率。进行亚组分析。采用随机效应法进行meta分析。乔安娜布里格斯研究所的流行率工具被用来评估纳入研究的偏倚风险。本系统综述和荟萃分析整合了来自24项研究的数据，包括4,272,805名参与者。SAP患病率为18.3% （95% CI: 13.7-23.0）。结论：我们的研究结果强调了有效识别和管理风险因素以降低SAP发生可能性的必要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Topics in Stroke Rehabilitation 医学-康复医学

CiteScore

5.10

自引率

4.50%

发文量

审稿时长

6-12 weeks

期刊介绍： Topics in Stroke Rehabilitation is the leading journal devoted to the study and dissemination of interdisciplinary, evidence-based, clinical information related to stroke rehabilitation. The journal’s scope covers physical medicine and rehabilitation, neurology, neurorehabilitation, neural engineering and therapeutics, neuropsychology and cognition, optimization of the rehabilitation system, robotics and biomechanics, pain management, nursing, physical therapy, cardiopulmonary fitness, mobility, occupational therapy, speech pathology and communication. There is a particular focus on stroke recovery, improving rehabilitation outcomes, quality of life, activities of daily living, motor control, family and care givers, and community issues. The journal reviews and reports clinical practices, clinical trials, state-of-the-art concepts, and new developments in stroke research and patient care. Both primary research papers, reviews of existing literature, and invited editorials, are included. Sharply-focused, single-issue topics, and the latest in clinical research, provide in-depth knowledge.