Follow-up Optical Coherence Tomography Evaluation of Endothelialization in Drug-eluting Stents for Symptomatic Vertebral Artery Stenosis: a Report of Nine Cases.

IF 3.2 3区医学 Q2 CLINICAL NEUROLOGY

Clinical Neuroradiology Pub Date : 2026-03-01 Epub Date: 2025-11-06 DOI:10.1007/s00062-025-01582-9

Bo Lei, Li Chen, Wenzhang Luo, Ying Chen, Honggang Wu, Jiachuan Wu, Shu Chen, Niandong Zheng, Daobao Zhang

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引用次数: 0

Abstract

Purpose: This study aimed to assess the endothelialization of drug-eluting stents (DES) 3 months after implantation for the treatment of symptomatic vertebral artery stenosis using endovascular optical coherence tomography (OCT).

Methods: Between March and May 2024, OCT was performed on patients 3 months (90 ± 7 days) after undergoing surgery for stent implantation at the vertebral artery ostium in our center.

Results: Nine DES were implanted in nine patients. The mean follow-up period was 95.6 ± 12.6 days. OCT findings showed the vertebral artery lumen with fully endothelialized stent struts covered by neointima in all nine patients 3 months after implantation, indicating complete endothelialization.

Conclusions: Complete endothelialization of vertebral artery DES occurred 3 months after implantation, providing a theoretical basis for potentially reducing the duration of DAPT 3 months. Further clinical studies are essential to validate these findings.

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9例临床症状性椎动脉狭窄药物洗脱支架内皮化的随访光学相干断层成像评价

目的：本研究旨在利用血管内光学相干断层扫描（OCT）评估药物洗脱支架（DES）植入3个月后治疗症状性椎动脉狭窄的内皮化情况。方法：于2024年3月至5月，对我院椎动脉口支架植入术后3个月（90 ±7天）的患者进行OCT检查。结果：9例患者共植入9枚DES。平均随访时间为95.6 ±12.6 d。9例患者在植入术3个月后，OCT结果均显示椎动脉腔内完全内皮化的支架支撑物被新生内膜覆盖，表明完全内皮化。结论：椎动脉DES在植入后3个月实现完全内皮化，为可能缩短DAPT持续时间3个月提供了理论依据。进一步的临床研究是验证这些发现的必要条件。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Neuroradiology CLINICAL NEUROLOGY-RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

CiteScore

5.00

自引率

3.60%

发文量

106

审稿时长

>12 weeks

期刊介绍： Clinical Neuroradiology provides current information, original contributions, and reviews in the field of neuroradiology. An interdisciplinary approach is accomplished by diagnostic and therapeutic contributions related to associated subjects. The international coverage and relevance of the journal is underlined by its being the official journal of the German, Swiss, and Austrian Societies of Neuroradiology.