Mistakes in the utilization of vibration-controlled transient elastography in the evaluation of liver fibrosis: a narrative review.

IF 3.3 3区医学 Q2 GASTROENTEROLOGY & HEPATOLOGY

Expert Review of Gastroenterology & Hepatology Pub Date : 2025-12-01 Epub Date: 2025-11-07 DOI:10.1080/17474124.2025.2586690

Madunil Anuk Niriella, Uditha Bandara Dassanayake, Charith Priyanga Madurapperuma, Indeewari Prathibha Wijesingha, Arjuna Priyadarshin De Silva, Hithnadura Janaka de Silva

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引用次数: 0

Abstract

Introduction: The degree of fibrosis is the most significant indicator of clinical prognosis in chronic liver disease (CLD). While liver biopsy remains the gold standard for assessing liver disease activity and fibrosis, its invasive nature, potential complications, and high cost have spurred the development of alternative diagnostic methods. This has led to significant interest in noninvasive, cost-effective, and easily replicable techniques for evaluating liver fibrosis. Among these noninvasive tests, vibration-controlled transient elastography (VCTE) has emerged as the most extensively researched and validated imaging-based method for staging liver fibrosis.

Areas covered: A selective literature search was conducted across electronic databases (PubMed, MEDLINE, Embase, and Cochrane Library) to identify relevant publications on VCTE. Randomized controlled trials, meta-analyses, systematic reviews, evidence-based clinical practice guidelines and selected expert consensus statements and narrative reviews were included.Given its increasing use, clinicians must know common pitfalls in VCTE applications when evaluating CLD. This review aims to outline these potential errors and provide evidence-based guidelines to help clinicians avoid them, thereby improving the accuracy and utility of VCTE in clinical practice.

Expert opinion: The future of VCTE involves improved accuracy, accessibility, and integration, leading to earlier detection and personalized management of CLD.

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应用振动控制瞬时弹性成像评价肝纤维化的错误：述评。

肝纤维化程度是慢性肝病（CLD）临床预后最重要的指标。虽然肝活检仍然是评估肝脏疾病活动性和纤维化的金标准，但其侵入性、潜在的并发症和高成本刺激了替代诊断方法的发展。这引起了对无创、低成本、易于复制的肝纤维化评估技术的极大兴趣。在这些无创测试中，振动控制瞬态弹性成像（VCTE）已成为研究最广泛和最有效的基于成像的肝纤维化分期方法。覆盖领域：通过电子数据库（PubMed， MEDLINE， Embase和Cochrane Library）进行选择性文献检索，以确定VCTE的相关出版物。包括随机对照试验、荟萃分析、系统评价、循证临床实践指南和选定的专家共识声明和叙述性评价。鉴于其越来越多的使用，临床医生在评估CLD时必须了解VCTE应用中的常见缺陷。本综述旨在概述这些潜在的错误，并提供循证指南，帮助临床医生避免这些错误，从而提高VCTE在临床实践中的准确性和实用性。专家意见：VCTE的未来包括提高准确性、可及性和集成度，从而实现CLD的早期检测和个性化管理。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Expert Review of Gastroenterology & Hepatology GASTROENTEROLOGY & HEPATOLOGY-

CiteScore

6.80

自引率

2.60%

发文量

审稿时长

6-12 weeks

期刊介绍： The enormous health and economic burden of gastrointestinal disease worldwide warrants a sharp focus on the etiology, epidemiology, prevention, diagnosis, treatment and development of new therapies. By the end of the last century we had seen enormous advances, both in technologies to visualize disease and in curative therapies in areas such as gastric ulcer, with the advent first of the H2-antagonists and then the proton pump inhibitors - clear examples of how advances in medicine can massively benefit the patient. Nevertheless, specialists face ongoing challenges from a wide array of diseases of diverse etiology.