Translational reinterpretation of ancestral healing rituals: Structured physiological modulation through adaptive biological responses

IF 2.4 4区医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE

Explore-The Journal of Science and Healing Pub Date : 2025-11-01 Epub Date: 2025-10-22 DOI:10.1016/j.explore.2025.103274

João Francisco Pollo Gaspary , Alfred Lee Edgar , Fernanda Peron Gaspary , Eduarda Grando Lopes , Luis Felipe Dias Lopes

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引用次数: 0

Abstract

Background

Ancestral healing rituals have long been embedded in cultural traditions as symbolic practices. However, emerging evidence suggests these rituals may act as structured behavioral interventions capable of eliciting adaptive physiological responses. This study proposes a translational reinterpretation of ancestral healing rituals through the lens of contemporary redox biology, systems physiology, and bioenergetic modulation.

Methods

Using a Work Breakdown Structure (WBS) and PRISMA-guided systematic reviews, the study was organized into five work packages (WP’s). Historical (WP2) and physiological (WP3) systematic reviews identified Fundamental Points of View (FPV’s) and Critical Success Factors (CSF’s). Heuristic triangulation in WP4 led to the emergence of the APEIC model (Adaptive Psychoneuroendocrineimmunometabolic Cascade), integrating behavioral practices with bioenergetic and metabolic processes. The model was validated in WP5 using SMART and FINER criteria.

Results

Five FPV’s (e.g., meditation, fasting, ritual celebration) and thirteen CSFs (e.g., redox modulation, neuroplasticity, immune adaptation) were identified. Findings suggest that rituals rhythmically modulate proton gradients, redox balance, and metabolic flexibility, contributing to systemic coherence. The APEIC model explains how ritual-induced stimuli can synchronize psychoneuroendocrine, immune, and metabolic systems via transient physiological oscillations. Endogenous DMT is proposed as a potential biomarker of integrative coherence.

Conclusion

Ancestral healing rituals can be reinterpreted as biologically plausible platforms for inducing adaptive physiological states. The APEIC model provides a conceptual foundation for non-pharmacological health strategies rooted in ancestral behavioral intelligence. Future studies should experimentally test the model’s mechanisms to inform integrative and personalized healthcare applications.

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祖先治疗仪式的翻译重新解释：通过适应性生物反应的结构化生理调节。

背景：祖先的治疗仪式长期以来一直作为象征性的实践嵌入文化传统中。然而，新出现的证据表明，这些仪式可能是一种结构化的行为干预，能够引发适应性的生理反应。本研究通过当代氧化还原生物学、系统生理学和生物能量调节的视角，提出了对祖先治疗仪式的翻译重新解释。方法：采用工作分解结构（WBS）和prisma引导的系统评价，将研究组织为五个工作包（WP’s）。历史（WP2）和生理（WP3）系统评价确定了基本观点（FPV）和关键成功因素（CSF）。WP4中的启发式三角测量导致了APEIC模型（适应性心理神经内分泌免疫代谢级联）的出现，将行为实践与生物能量和代谢过程结合起来。采用SMART和FINER标准在WP5中对模型进行验证。结果：鉴定出5种FPV（如冥想、禁食、仪式庆祝）和13种csf（如氧化还原调节、神经可塑性、免疫适应）。研究结果表明，仪式有节奏地调节质子梯度、氧化还原平衡和代谢灵活性，有助于系统一致性。APEIC模型解释了仪式诱导的刺激如何通过短暂的生理振荡使心理神经内分泌、免疫和代谢系统同步。内源性DMT被认为是整合一致性的潜在生物标志物。结论：祖先的治疗仪式可以被重新解释为诱导适应性生理状态的生物学可信平台。APEIC模型为植根于祖先行为智力的非药物健康策略提供了概念基础。未来的研究应该通过实验测试该模型的机制，为综合和个性化医疗保健应用提供信息。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Explore-The Journal of Science and Healing 医学-全科医学与补充医学

CiteScore

3.00

自引率

8.30%

发文量

179

审稿时长

25 days

期刊介绍： EXPLORE: The Journal of Science & Healing addresses the scientific principles behind, and applications of, evidence-based healing practices from a wide variety of sources, including conventional, alternative, and cross-cultural medicine. It is an interdisciplinary journal that explores the healing arts, consciousness, spirituality, eco-environmental issues, and basic science as all these fields relate to health.