Meta-analysis of yoga-based mind-body interventions in the management of inflammatory bowel disease

IF 4 3区医学 Q1 INTEGRATIVE & COMPLEMENTARY MEDICINE

Complementary therapies in medicine Pub Date : 2025-12-01 Epub Date: 2025-11-01 DOI:10.1016/j.ctim.2025.103287

Linjia Pan , Xiaotong Chen , Yiqi Wu , Zhanyi Zhou , Daogun Xu

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引用次数: 0

Abstract

Background

Inflammatory bowel disease (IBD) affects millions worldwide and imposes both physical and psychological burdens. While current treatments have limitations, yoga-based mind-body interventions (YMBIs) show promise in improving symptoms and quality of life through physiological and stress-regulating pathways.

Objective

This Meta-analysis seeks to comprehensively and objectively assess the efficacy of yoga-based mind-body interventions on psychological, physical, and inflammatory outcomes in patients with IBD.

Methods

A comprehensive search was conducted in both international and Chinese databases including PubMed, EMBASE, Cochrane Library, Web of Science, Medline, China National Knowledge Infrastructure (CNKI), WanFang, and China Biomedical Literature Service System. Randomized controlled trials (RCTs) comparing YMBIs with standard care or placebo in IBD patients were pooled from inception to February 17, 2025. Data were analyzed using RevMan 5.4 and Stata 16.0, with standardized mean differences (SMDs) and 95 % confidence intervals (CIs) as effect measures.

Results

Seven RCTs comprising 502 participants were included. The meta-analysis revealed that YMBIs significantly reduced anxiety (SMD = −0.56, 95 % CI [−0.77 to −0.36], P < 0.0001), depression (SMD = −3.45, 95 % CI [−5.52 to −1.37], P < 0.0001), and perceived stress (SMD = −0.70, 95 % CI [−1.00 to −0.39], P < 0.0001), while improving quality of life (SMD = 0.47, 95 % CI [0.17–0.77], P = 0.002). Effects on sleep quality (SMD = −1.98, 95 % CI [−3.98–0.02], P = 0.05) and disease activity (SMD = −0.26, 95 % CI [−0.52–0.01], P = 0.05) were modest, with borderline statistical significance.

Conclusion

YMBIs alleviates psychological distress and enhance well-being in IBD patients, though their impact on disease progression remains uncertain. However, their effects on sleep quality and disease activity require further validation through high-quality clinical studies.

Systematic review registration

https://www.crd.york.ac.uk/PROSPERO/view/CRD420250653339.

查看原文本刊更多论文

以瑜伽为基础的心身干预治疗炎症性肠病的meta分析

背景：炎症性肠病（IBD）影响着全世界数百万人，并给他们带来身体和心理上的负担。虽然目前的治疗方法有局限性，但基于瑜伽的身心干预（YMBIs）显示出通过生理和压力调节途径改善症状和生活质量的希望。目的：本荟萃分析旨在全面客观地评估基于瑜伽的身心干预对IBD患者心理、身体和炎症结局的疗效。方法：综合检索PubMed、EMBASE、Cochrane Library、Web of Science、Medline、中国知网、万方、中国生物医学文献服务系统等国内外数据库。比较IBD患者中YMBIs与标准治疗或安慰剂的随机对照试验（rct）从开始到2025年2月17日进行汇总。采用RevMan 5.4和Stata 16.0对数据进行分析，以标准化平均差异（SMDs）和95%置信区间（ci）作为效果度量。结果：纳入7项随机对照试验，共502名受试者。荟萃分析显示，YMBIs显著降低了焦虑（SMD = -0.56, 95% CI [-0.77 ~ -0.36], P < 0.0001）、抑郁（SMD = -3.45, 95% CI [-5.52 ~ -1.37], P < 0.0001）和感知压力（SMD = -0.70, 95% CI [-1.00 ~ -0.39], P < 0.0001），同时改善了生活质量（SMD = 0.47, 95% CI [0.17 ~ 0.77], P = 0.002）。对睡眠质量（SMD = -1.98, 95% CI [-3.98 ~ 0.02], P = 0.05）和疾病活动性（SMD = -0.26, 95% CI [-0.52 ~ 0.01], P = 0.05）的影响一般，具有临界统计学意义。结论：YMBIs可减轻IBD患者的心理困扰，提高幸福感，但其对疾病进展的影响尚不确定。然而，它们对睡眠质量和疾病活动的影响需要通过高质量的临床研究进一步验证。系统评审注册：https://www.crd.york.ac.uk/PROSPERO/view/CRD420250653339。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Complementary therapies in medicine 医学-全科医学与补充医学

CiteScore

8.60

自引率

2.80%

发文量

101

审稿时长

112 days

期刊介绍： Complementary Therapies in Medicine is an international, peer-reviewed journal that has considerable appeal to anyone who seeks objective and critical information on complementary therapies or who wishes to deepen their understanding of these approaches. It will be of particular interest to healthcare practitioners including family practitioners, complementary therapists, nurses, and physiotherapists; to academics including social scientists and CAM researchers; to healthcare managers; and to patients. Complementary Therapies in Medicine aims to publish valid, relevant and rigorous research and serious discussion articles with the main purpose of improving healthcare.