Toxina botulínica perineural en el tratamiento de la cefalea postraumática. Caso clínico

IF 1.3 Q3 ANESTHESIOLOGY
L. Arce Gálvez , J.M. Mancera Álzate
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引用次数: 0

Abstract

Post-traumatic headache is a common condition that can be managed with pharmacologic interventions or analgesic procedures; however, most evidence is derived from patients with mild trauma, leaving a large gap with regard to patients with moderate or severe trauma who present complex pain. Botulinum toxin plays an increasingly important role in pain management. This neurotoxin acts on different receptors, ranging from TRPV1 (transient receptor potential vanilloid type 1) to CGRP (calcitonin gene-related peptide). This is the first case report of the use of perineural botulinum toxin in a patient with moderate post-traumatic headache who responded poorly to standard interventional measures.
神经周围肉毒杆菌毒素治疗创伤后头痛。临床病例
创伤后头痛是一种常见疾病,可通过药物干预或镇痛程序加以控制;然而,大多数证据来自轻度创伤患者,对于出现复杂疼痛的中度或重度创伤患者,存在很大的差距。肉毒杆菌毒素在疼痛管理中扮演着越来越重要的角色。这种神经毒素作用于不同的受体,从TRPV1(瞬时受体电位1型香草素)到CGRP(降钙素基因相关肽)。这是首例使用神经周肉毒杆菌毒素治疗中度创伤后头痛患者的病例报告,该患者对标准干预措施反应不佳。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
1.80
自引率
15.40%
发文量
113
审稿时长
82 days
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