Right ventricular pressure-volume loop analysis in congenital heart disease

IF 1.5 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS

International journal of cardiology. Congenital heart disease Pub Date : 2025-12-01 Epub Date: 2025-10-02 DOI:10.1016/j.ijcchd.2025.100625

Renée S. Joosen , Michael G. Dickinson , Marielle C. van de Veerdonk , Rahi S. Alipour Symakani , Daphne Merkus , Michiel Voskuil , Gregor J. Krings , Johannes M.P.J. Breur

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Abstract

Background

Right ventricular (RV) function is an independent predictor of prognosis in patients with congenital heart disease (CHD). Early detection is therefore crucial but current methods to assess RV function are highly load-dependent. RV pressure-volume (PV) loop analysis is an invasive technique which is load-independent and considered the gold standard for evaluating RV adaptation in relation to its load. However, RV PV loop analysis can be time consuming and prone to inter-operator variability.

Methods

This article provides a comprehensive guide on performing RV PV loop analysis using the multi-beat method in pediatric and adult patients with complex CHD.

Results

RV PV loop analysis using the multi-beat method can be safely and reliably applied in children and adults with complex CHD.

Conclusion

RV PV loop analysis offers a valuable tool for advanced insight into RV adaptation and a deeper understanding of cardiac physiology in complex CHD patients with RV pressure and/or volume overload. By enhancing our understanding of RV adaptation, this approach holds great potential for improving patient management and optimizing treatment strategies.

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先天性心脏病右心室压力-容积环分析

背景：右心室（RV）功能是先天性心脏病（CHD）患者预后的独立预测因子。因此，早期检测至关重要，但目前评估右心室功能的方法高度依赖于负荷。RV压力-体积（PV）环分析是一种与负荷无关的侵入性技术，被认为是评估RV与负荷相关的适应性的金标准。然而，RV PV回路分析可能是耗时的，并且容易受到操作者之间的变化。方法采用多拍法对儿童和成人复杂冠心病患者进行RV - PV环路分析。结果采用多拍法进行rv PV环路分析可安全可靠地应用于儿童和成人复杂冠心病患者。结论右心室PV环分析为深入了解右心室适应和更深入地了解右心室压力和/或容量过载的复杂冠心病患者的心脏生理提供了有价值的工具。通过增强我们对RV适应的理解，这种方法在改善患者管理和优化治疗策略方面具有巨大的潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International journal of cardiology. Congenital heart disease Cardiology and Cardiovascular Medicine

自引率

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审稿时长

83 days