Herbal remedies from Persian medicine for relieving fatigue: A systematic review

IF 1.4 Q2 Medicine

Advances in integrative medicine Pub Date : 2025-12-01 Epub Date: 2025-10-16 DOI:10.1016/j.aimed.2025.100585

Ata Amani , Bayazid Ghaderi , Mehdi Pasalar , Ali Kashkooe , Mohammad Mehdi Zarshenas , Reza Tabrizi , Thomas Rampp , Ghazaleh Heydarirad

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引用次数: 0

Abstract

Introduction

Fatigue is a common issue affecting individuals from diverse backgrounds, often leading to a decrease in overall health. Numerous foods, including medicinal plants, possess properties that help combat fatigue through two main mechanisms: antioxidant and anti-inflammatory effects. We aimed to explore the knowledge and potential of herbal medicines originated from Persian medicine (PM) in relieving fatigue.

Methods

This systematic review used a thorough search strategy, examining various historical Persian Medicine textbooks and electronic databases in both Persian and English. Herbal remedies that met the inclusion criteria were considered, particularly those exhibiting antioxidant and anti-inflammatory properties. Data from selected studies were extracted and thematically synthesized.

Results

A total of 49 herbal medicines were identified from Persian Medicine, showcasing varying temperaments. Among 44 articles meeting inclusion criteria, clinical trials demonstrated the effectiveness of several herbs, including Acacia arabica, Brassica rapa, Camellia sinensis, and Coffea arabica, in alleviating fatigue in humans. Additionally, Areca catechu and Phoenix dactylifera were effective in animal studies. The included articles assessed the methods and mechanisms of action for all herbal preparations, illuminating their anti-fatigue properties and the quality of supporting evidence.

Conclusions

Various herbs showed potential anti-fatigue properties in humans and animals, emphasizing the role of traditional modalities like PM. While further research is essential to validate and understand these effects, the identified herbs show potential for providing relief from fatigue.

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波斯医学缓解疲劳的草药疗法：系统回顾

疲劳是一个影响不同背景的人的普遍问题，经常导致整体健康状况下降。许多食物，包括药用植物，都具有通过两种主要机制来对抗疲劳的特性：抗氧化和抗炎作用。我们的目的是探索波斯医学草药在缓解疲劳方面的知识和潜力。方法本系统综述采用了全面的检索策略，检查了各种波斯医学历史教科书和波斯语和英语电子数据库。符合纳入标准的草药被考虑，特别是那些表现出抗氧化和抗炎特性的草药。从选定的研究中提取数据并按主题进行综合。结果从波斯医学中鉴定出49种中草药，表现出不同的气质。在44篇符合纳入标准的文章中，临床试验证明了几种草药的有效性，包括阿拉伯相思、油菜、茶花和阿拉比卡咖啡，可以缓解人类的疲劳。此外，槟榔和凤凰花在动物实验中也有效。纳入的文章评估了所有草药制剂的方法和作用机制，阐明了它们的抗疲劳性能和支持证据的质量。结论多种中药对人体和动物均有潜在的抗疲劳作用，强调了传统中药如PM的作用。虽然进一步的研究对验证和理解这些影响是必要的，但已确定的草药显示出缓解疲劳的潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Advances in integrative medicine INTEGRATIVE & COMPLEMENTARY MEDICINE-

CiteScore

3.20

自引率

11.80%

发文量

审稿时长

15 weeks

期刊介绍： Advances in Integrative Medicine (AIMED) is an international peer-reviewed, evidence-based research and review journal that is multi-disciplinary within the fields of Integrative and Complementary Medicine. The journal focuses on rigorous quantitative and qualitative research including systematic reviews, clinical trials and surveys, whilst also welcoming medical hypotheses and clinically-relevant articles and case studies disclosing practical learning tools for the consulting practitioner. By promoting research and practice excellence in the field, and cross collaboration between relevant practitioner groups and associations, the journal aims to advance the practice of IM, identify areas for future research, and improve patient health outcomes. International networking is encouraged through clinical innovation, the establishment of best practice and by providing opportunities for cooperation between organisations and communities.