Unilateral Acroangiodermatitis: From Histopathologic Confirmation to Treatment with PDL.

IF 1.8 Q3 DERMATOLOGY
André Aparício Martins, José Carlos Cardoso, André Pinho
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引用次数: 0

Abstract

Acroangiodermatitis is an uncommon angioproliferative dermatosis, related to chronic circulatory diseases, such as chronic venous insufficiency and arteriovenous malformations. We describe the case of a 32-year-old healthy male presenting with a pruritic, brownish lesion on the dorsal surface of the left foot, evolving for ten years. Physical examination revealed a brown plaque, with a verrucous surface, on the distal dorsum and medial border of the left foot. Histopathology disclosed a marked neovascularization of the upper dermis, associated with erythrocyte extravasation and hemosiderin deposition. Immunochemistry for HHV-8 was negative. CT angiography revealed multiple serpiginous vessels on the dorsum of the left foot, suggestive of a venous malformation. The diagnosis of acroangiodermatitis was established and the patient started topical corticosteroids and compression stockings, without improvement. Although scarcely described in the literature, treatment with PDL was proposed given the vascular proliferation confined to the papillary dermis. After two sessions, a significant improvement was observed. This case emphasises dermatopathology as the gold standard for the differential diagnosis with Kaposi sarcoma. In addition, it highlights PDL as a promising therapeutic option, based on the superficial histopathological location.

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单侧肢端血管皮炎:从组织病理学证实到PDL治疗。
肢端血管皮炎是一种罕见的血管增生性皮肤病,与慢性静脉功能不全、动静脉畸形等慢性循环系统疾病有关。我们描述的情况下,一个32岁的健康男性表现为瘙痒,棕色病变的背表面的左脚,演变十年。体格检查发现左脚远端背侧和内侧边界有一棕色斑块,表面呈疣状。组织病理学显示真皮上部有明显的新生血管形成,与红细胞外渗和含铁血黄素沉积有关。HHV-8免疫化学阴性。CT血管造影显示左脚背多处蛇形血管,提示静脉畸形。确诊为肢端血管皮炎后,患者开始使用局部皮质类固醇和压迫袜,但没有改善。虽然在文献中几乎没有描述,但考虑到血管增殖局限于乳头状真皮,提出了PDL治疗。两个疗程后,观察到明显的改善。本病例强调皮肤病理是鉴别卡波西肉瘤的金标准。此外,它强调PDL作为一个有前途的治疗选择,基于表面组织病理学位置。
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来源期刊
Dermatopathology
Dermatopathology DERMATOLOGY-
自引率
5.30%
发文量
39
审稿时长
11 weeks
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