Amended Safety Assessment of Silicates as Used in Cosmetics.

IF 1 4区 医学 Q4 PHARMACOLOGY & PHARMACY
Christina L Burnett, Wilma F Bergfeld, Donald V Belsito, David E Cohen, Curtis D Klaassen, Daniel C Liebler, James G Marks, Lisa A Peterson, Ronald C Shank, Thomas J Slaga, Paul W Snyder, Monice M Fiume, Bart Heldreth
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引用次数: 0

Abstract

The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of 24 silicate ingredients that are solid inorganic oxides, comprising, in part, silicon dioxide, which can be derived from naturally occurring minerals or can be produced synthetically. Reported functions in cosmetics include abrasives, absorbents, bulking agents, and deodorant agents. The Panel reviewed all relevant data and concluded that the silicate ingredients are safe in cosmetics in the present practices of use and concentration described in this safety assessment when formulated to be non-irritating, with the exception that the available data are insufficient to make a determination of safety for the use of naturally sourced (i.e., mined) silicate ingredients in products that may be incidentally inhaled.

修订了化妆品用硅酸盐的安全性评价。
化妆品成分安全专家小组(专家小组)评估了24种硅酸盐成分的安全性,这些成分是固体无机氧化物,部分由二氧化硅组成,可以从天然矿物中提取,也可以合成。据报道,其在化妆品中的作用包括磨料、吸收剂、膨胀剂和除臭剂。评估小组审查了所有相关数据,得出结论认为,按照本安全评估中所述的目前使用方法和浓度,当配制成无刺激性时,硅酸盐成分在化妆品中的使用是安全的,但现有数据不足以确定在产品中使用可能偶然吸入的天然来源(即开采)硅酸盐成分的安全性。
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来源期刊
CiteScore
3.40
自引率
4.50%
发文量
53
审稿时长
4.5 months
期刊介绍: The International Journal of Toxicology publishes timely, peer-reviewed papers on current topics important to toxicologists. Six bi-monthly issues cover a wide range of topics, including contemporary issues in toxicology, safety assessments, novel approaches to toxicological testing, mechanisms of toxicity, biomarkers, and risk assessment. The Journal also publishes invited reviews on contemporary topics, and features articles based on symposia. In addition, supplemental issues are routinely published on various special topics, including three supplements devoted to contributions from the Cosmetic Review Expert Panel.
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