Rethinking tractography and neuroanatomy: does image resolution hold the key?

IF 2.9 3区医学 Q1 ANATOMY & MORPHOLOGY

Brain Structure & Function Pub Date : 2025-10-23 DOI:10.1007/s00429-025-03025-0

Tim B Dyrby, Laurent Petit, Christian Beaulieu

引用次数: 0

Abstract

The structural brain connectome spans multiple length scales with varying complexity, from major commissural, association, and projection pathways down to much smaller pathways within brain regions. Diffusion MRI is often acquired for whole-brain coverage with limited spatial resolution for tractography purposes. How does this 'one size fits all' approach impact tractography and diffusion quantification, and do we need to care? Here, we discuss the concept of image resolution and define the structural image resolution limit, representing the resolution threshold at which a given dMRI setup can reliably resolve anatomical structures.

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重新思考神经束造影和神经解剖学：图像分辨率是关键吗？

结构脑连接组跨越多个长度尺度，具有不同的复杂性，从主要的连接、关联和投射通路到大脑区域内更小的通路。弥散MRI通常用于全脑覆盖，空间分辨率有限，用于神经束造影。这种“一刀切”的方法如何影响导管造影和扩散量化，我们是否需要关心？在这里，我们讨论了图像分辨率的概念，并定义了结构图像分辨率极限，表示给定dMRI设置可以可靠地解析解剖结构的分辨率阈值。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Brain Structure & Function 医学-解剖学与形态学

CiteScore

6.00

自引率

6.50%

发文量

168

审稿时长

8 months

期刊介绍： Brain Structure & Function publishes research that provides insight into brain structure−function relationships. Studies published here integrate data spanning from molecular, cellular, developmental, and systems architecture to the neuroanatomy of behavior and cognitive functions. Manuscripts with focus on the spinal cord or the peripheral nervous system are not accepted for publication. Manuscripts with focus on diseases, animal models of diseases, or disease-related mechanisms are only considered for publication, if the findings provide novel insight into the organization and mechanisms of normal brain structure and function.