Beating-wave analysis of small-angle X-ray scattering of unilamellar liposomes loaded with model drug Benzocaine.

IF 5.1 3区材料科学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Nanoscale Pub Date : 2025-10-23 DOI:10.1039/d5nr01468a

Laura Baraldi,Serena R Alfarano,Flávia Sousa,Luciano Marchiò,Alessia Bacchi,Raffaele Mezzenga,Barbara Rothen-Rutishauser,Alke Petri-Fink,Sandor Balog

引用次数: 0

Abstract

A robust mathematical model was developed to characterize the liposomal bilayer via small-angle X-ray scattering (SAXS). The model was tested on four liposome formulations having the same excipients but different loaded drugs, demonstrating high accuracy in drawing the electron density profiles, highlighting their differences.

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载模型药物苯佐卡因单层脂质体小角x射线散射的拍打波分析。

建立了一个稳健的数学模型，通过小角x射线散射（SAXS）来表征脂质体双分子层。该模型在四种具有相同赋形剂但装载不同药物的脂质体配方中进行了测试，显示出绘制电子密度曲线的高精度，突出了它们的差异。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nanoscale CHEMISTRY, MULTIDISCIPLINARY-NANOSCIENCE & NANOTECHNOLOGY

CiteScore

12.10

自引率

3.00%

发文量

1628

审稿时长

1.6 months

期刊介绍： Nanoscale is a high-impact international journal, publishing high-quality research across nanoscience and nanotechnology. Nanoscale publishes a full mix of research articles on experimental and theoretical work, including reviews, communications, and full papers.Highly interdisciplinary, this journal appeals to scientists, researchers and professionals interested in nanoscience and nanotechnology, quantum materials and quantum technology, including the areas of physics, chemistry, biology, medicine, materials, energy/environment, information technology, detection science, healthcare and drug discovery, and electronics.