Biomechanical Impact of Partitioning Position and Angle on Post-SPGJ Gastric Emptying.

IF 4.8 3区 综合性期刊 Q1 MULTIDISCIPLINARY SCIENCES
Zhenmin Fan,Qiuliang Li,Fengyan Xu,Haiqiao Zhang,Xia Ye,Zhi Zheng,Jun Zhang
{"title":"Biomechanical Impact of Partitioning Position and Angle on Post-SPGJ Gastric Emptying.","authors":"Zhenmin Fan,Qiuliang Li,Fengyan Xu,Haiqiao Zhang,Xia Ye,Zhi Zheng,Jun Zhang","doi":"10.1111/nyas.70104","DOIUrl":null,"url":null,"abstract":"Stomach-partitioning gastrojejunostomy (SPGJ) improves gastric-outlet obstruction outcomes, yet its biomechanical basis and geometric optimization remain unclear. Patient computed tomography (CT) data were used to reconstruct realistic SPGJ models. Computational fluid dynamics combined with a discrete phase model quantified velocity, wall pressure, particle-retention time, and velocity under systematic variations of partitioning position (distal, mid, and proximal), partitioning angle (5°, 15°, and 25°; left- or right-sided), and incision angle (60°, 75°, and 90°). Distal partitioning produced the lowest pressure drop and fastest emptying, whereas proximal partitioning channeled high-speed flow toward the pylorus and prolonged retention. A ∼15° partitioning angle balanced flow restriction and clearance; extreme unilateral angles either increased particle stasis (left-side) or slowed emptying despite reduced reflux (right-side). A vertical incision (90°) further decreased pressure losses and shortened mean retention relative to oblique cuts. SPGJ biomechanics are highly geometry-sensitive. Distal placement, a 15° partitioning angle, and a near-vertical incision collectively optimize flow, reduce lesion contact, and accelerate gastric emptying, providing quantitative guidance for patient-specific SPGJ design.","PeriodicalId":8250,"journal":{"name":"Annals of the New York Academy of Sciences","volume":"53 1","pages":""},"PeriodicalIF":4.8000,"publicationDate":"2025-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of the New York Academy of Sciences","FirstCategoryId":"103","ListUrlMain":"https://doi.org/10.1111/nyas.70104","RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MULTIDISCIPLINARY SCIENCES","Score":null,"Total":0}
引用次数: 0

Abstract

Stomach-partitioning gastrojejunostomy (SPGJ) improves gastric-outlet obstruction outcomes, yet its biomechanical basis and geometric optimization remain unclear. Patient computed tomography (CT) data were used to reconstruct realistic SPGJ models. Computational fluid dynamics combined with a discrete phase model quantified velocity, wall pressure, particle-retention time, and velocity under systematic variations of partitioning position (distal, mid, and proximal), partitioning angle (5°, 15°, and 25°; left- or right-sided), and incision angle (60°, 75°, and 90°). Distal partitioning produced the lowest pressure drop and fastest emptying, whereas proximal partitioning channeled high-speed flow toward the pylorus and prolonged retention. A ∼15° partitioning angle balanced flow restriction and clearance; extreme unilateral angles either increased particle stasis (left-side) or slowed emptying despite reduced reflux (right-side). A vertical incision (90°) further decreased pressure losses and shortened mean retention relative to oblique cuts. SPGJ biomechanics are highly geometry-sensitive. Distal placement, a 15° partitioning angle, and a near-vertical incision collectively optimize flow, reduce lesion contact, and accelerate gastric emptying, providing quantitative guidance for patient-specific SPGJ design.
分块位置和角度对spgj后胃排空的生物力学影响。
胃分区胃空肠吻合术(SPGJ)改善了胃出口梗阻的预后,但其生物力学基础和几何优化尚不清楚。使用患者计算机断层扫描(CT)数据重建真实的SPGJ模型。结合离散相模型的计算流体动力学量化了在系统变化的分区位置(远端、中端和近端)、分区角度(5°、15°和25°;左侧或右侧)和切口角度(60°、75°和90°)下的速度、壁面压力、颗粒滞留时间和速度。远端分块产生最小的压降和最快的排空,而近端分块引导高速血流向幽门和延长潴留。1 ~ 15°分配角平衡流动限制和间隙;极端的单侧角度要么增加颗粒停滞(左侧),要么减缓排空,尽管反流减少(右侧)。与斜切口相比,垂直切口(90°)进一步降低了压力损失,缩短了平均滞留时间。SPGJ生物力学是高度几何敏感的。远端放置、15°分割角和近垂直切口共同优化流量,减少病灶接触,加速胃排空,为患者特异性SPGJ设计提供定量指导。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Annals of the New York Academy of Sciences
Annals of the New York Academy of Sciences 综合性期刊-综合性期刊
CiteScore
11.00
自引率
1.90%
发文量
193
审稿时长
2-4 weeks
期刊介绍: Published on behalf of the New York Academy of Sciences, Annals of the New York Academy of Sciences provides multidisciplinary perspectives on research of current scientific interest with far-reaching implications for the wider scientific community and society at large. Each special issue assembles the best thinking of key contributors to a field of investigation at a time when emerging developments offer the promise of new insight. Individually themed, Annals special issues stimulate new ways to think about science by providing a neutral forum for discourse—within and across many institutions and fields.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信