Evolving Decongestion Strategies in the Management of Acute Heart Failure.

IF 1.1 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS

Current Treatment Options in Cardiovascular Medicine Pub Date : 2025-01-01 Epub Date: 2025-10-18 DOI:10.1007/s11936-025-01125-y

Jeffrey George, W H Wilson Tang

{"title":"Evolving Decongestion Strategies in the Management of Acute Heart Failure.","authors":"Jeffrey George, W H Wilson Tang","doi":"10.1007/s11936-025-01125-y","DOIUrl":null,"url":null,"abstract":"Purpose of review: To provide an overview of the latest evidence-based treatment strategies for acute heart failure (HF), with a significant focus on recent clinical trials and their associated implications within clinical practice.Recent findings: Recent studies have highlighted the effectiveness of urine sodium-guided decongestion, segmental nephron blockade, disease-modifying therapies, and the use of maintenance diuretics. These approaches have demonstrated significant improvements in patient outcomes, including better decongestion, reduced hospital admissions, and improved survival rates.Summary: The findings suggest a multifaceted, evidence-based approach is necessary for the effective management of acute HF. Implementing urine sodium-guided decongestion and segmental nephron blockade can enhance diuretic efficiency while disease-modifying therapies improve long-term outcomes. Maintenance diuretics play a crucial role in preventing recurrent hospitalizations.","PeriodicalId":35912,"journal":{"name":"Current Treatment Options in Cardiovascular Medicine","volume":"27 1","pages":"71"},"PeriodicalIF":1.1000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12535541/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Treatment Options in Cardiovascular Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/s11936-025-01125-y","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/10/18 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}

引用次数: 0

Abstract

Purpose of review: To provide an overview of the latest evidence-based treatment strategies for acute heart failure (HF), with a significant focus on recent clinical trials and their associated implications within clinical practice.

Recent findings: Recent studies have highlighted the effectiveness of urine sodium-guided decongestion, segmental nephron blockade, disease-modifying therapies, and the use of maintenance diuretics. These approaches have demonstrated significant improvements in patient outcomes, including better decongestion, reduced hospital admissions, and improved survival rates.

Summary: The findings suggest a multifaceted, evidence-based approach is necessary for the effective management of acute HF. Implementing urine sodium-guided decongestion and segmental nephron blockade can enhance diuretic efficiency while disease-modifying therapies improve long-term outcomes. Maintenance diuretics play a crucial role in preventing recurrent hospitalizations.

Abstract Image

查看原文本刊更多论文

急性心力衰竭管理中不断发展的去充血策略。

综述的目的：概述最新的急性心力衰竭（HF）循证治疗策略，重点关注最近的临床试验及其在临床实践中的相关意义。最近的发现：最近的研究强调了尿钠引导下的去充血、节段性肾元阻断、疾病修饰疗法和使用维护性利尿剂的有效性。这些方法已证明在患者预后方面有显著改善，包括更好地缓解拥堵、减少住院率和提高生存率。总结：研究结果表明，要有效管理急性心衰，需要采用多方面的、循证的方法。实施尿钠引导下的去充血和节段性肾元阻断可以提高利尿效率，而疾病改善疗法可以改善长期预后。维持利尿剂在预防复发住院中起着至关重要的作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Current Treatment Options in Cardiovascular Medicine Medicine-Cardiology and Cardiovascular Medicine

CiteScore

2.00

自引率

0.00%

发文量

期刊介绍： This journal aims to review the most important, recently published treatment-related advances in cardiovascular medicine. By providing clear, insightful, balanced contributions by international experts, the journal intends to elucidate novel approaches to treatment in those affected by the spectrum of cardiovascular-related diseases and conditions. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas, such as coronary artery disease, cerebrovascular disease and stroke, heart failure, pediatric and congenital heart disease, and valvular, myocardial, pericardial, and cardiopulmonary diseases. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. We also provide commentaries from well-known figures in the field, and an international Editorial Board reviews the annual table of contents, suggests articles of special interest to their country/region, and ensures that topics are current and include emerging research.