Fast and easy reactor-based production of copper-64 with high molar activities using recoil chemistry.

IF 3.3 3区化学 Q2 CHEMISTRY, INORGANIC & NUCLEAR

Dalton Transactions Pub Date : 2025-10-21 DOI:10.1039/d5dt02046h

Martin Pressler,Christoph Denk,Hannes Mikula,Veronika Rosecker

引用次数: 0

Abstract

Reactor-based production of medically relevant 64Cu is only possible using recoil chemistry. We report highly soluble tert-butyl copper(II) phthalocyanine as the target material. This enables efficient 64Cu recovery through liquid-liquid extraction after neutron capture. The automatable process allows reuse of the target material and achieves a molar activity of 950 MBq μmol-1.

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利用反冲化学快速简便地以反应器为基础生产具有高摩尔活性的64铜。

基于反应堆的医学相关64Cu生产只能使用反冲化学。我们报道了高可溶性叔丁基铜（II）酞菁作为目标材料。这使得中子捕获后通过液-液萃取有效地回收64Cu。自动化过程允许重复使用目标材料，并实现950 MBq μmol-1的摩尔活性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Dalton Transactions 化学-无机化学与核化学

CiteScore

6.60

自引率

7.50%

发文量

1832

审稿时长

1.5 months

期刊介绍： Dalton Transactions is a journal for all areas of inorganic chemistry, which encompasses the organometallic, bioinorganic and materials chemistry of the elements, with applications including synthesis, catalysis, energy conversion/storage, electrical devices and medicine. Dalton Transactions welcomes high-quality, original submissions in all of these areas and more, where the advancement of knowledge in inorganic chemistry is significant.