Electrochemical Detection of Melatonin in the Presence of Dopamine on a Ce-Doped Poly(bromocresol purple)-Modified Electrode

IF 4.3 3区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

ACS Omega Pub Date : 2025-10-09 DOI:10.1021/acsomega.5c04226

Hülya Öztürk Doğan*, , , Neslihan Çelebi*, , and , Arzu Kavaz Yüksel,

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Abstract

In this study, bromocresol purple was electropolymerized on the surface of a pencil graphite electrode (PGE) and electrochemically doped with cerium (Ce) nanoparticles. The Ce-doped poly(bromocresol purple) (Ce/PBCP)-modified PGE was characterized using energy dispersive X-ray spectroscopy, scanning electron microscopy, and X-ray photoelectron spectroscopy. The prepared Ce/PBCP electrode was investigated for the electrochemical determination of melatonin in the presence of dopamine. The electrochemical activity of the Ce/PBCP electrode was compared with that of undoped PBCP, Ce/PGE, and bare PGE. The peak potential and peak current for melatonin oxidation were +800 mV and 820 μA cm^–2, respectively. The detection limit of melatonin was 0.038 μM, and the Ce/PBCP electrode exhibited high activity in the presence of interfering species. In addition, the use of a Ce/PBCP electrode for detecting melatonin in a terebinth sample, a real food sample, was also investigated, and the produced electrode demonstrated high performance.

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在掺杂铈的聚溴甲酚紫修饰电极上电化学检测多巴胺存在下的褪黑激素

在这项研究中，溴甲酚紫色在铅笔石墨电极（PGE）表面电聚合，并电化学掺杂铈（Ce）纳米粒子。采用能量色散x射线能谱、扫描电镜和x射线光电子能谱对Ce掺杂聚溴甲酚紫（Ce/PBCP）改性PGE进行了表征。研究了制备的Ce/PBCP电极在多巴胺存在下对褪黑激素的电化学测定。比较了Ce/PBCP电极与未掺杂PBCP、Ce/PGE和裸PGE电极的电化学活性。褪黑素氧化峰电位和峰电流分别为+800 mV和820 μA cm-2。Ce/PBCP电极对褪黑素的检出限为0.038 μM，在干扰物质存在下具有较高的活性。此外，还研究了Ce/PBCP电极用于检测三分之一样品（一种真正的食品样品）中的褪黑激素，并证明了所生产的电极的高性能。

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来源期刊

ACS Omega Chemical Engineering-General Chemical Engineering

CiteScore

6.60

自引率

4.90%

发文量

3945

审稿时长

2.4 months

期刊介绍： ACS Omega is an open-access global publication for scientific articles that describe new findings in chemistry and interfacing areas of science, without any perceived evaluation of immediate impact.