Sound preferences in mice are sex dependent.

IF 6.9 1区 生物学 Q1 CELL BIOLOGY
Kamini Sehrawat, Israel Nelken
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引用次数: 0

Abstract

We investigated the impact of early exposure to sound and to silence on sound preferences later in life in mice. We exposed young mice during the critical periods to excerpts of music (first movement of Beethoven's symphony no. 9), non-music sounds, or to silence. We tested the sound preference behavior a few weeks later. Exposure affects mouse behavior in a sex-dependent manner: for example, male mice, but not female mice, exposed to silence show robust preference to silence relative to their naive controls. The neural activity in the auditory cortex is suppressed in mice exposed to either music or silence compared to naive controls. Remarkably, a robust negative correlation is found between neural response and sound preferences in female, but not in male, mice.

老鼠的声音偏好与性别有关。
我们研究了早期接触声音和沉默对小鼠以后生活中声音偏好的影响。在关键时期,我们让年轻的老鼠听一些音乐片段(贝多芬交响曲第一乐章)。9)、非音乐之声,还是归于寂静。几周后,我们测试了声音偏好行为。暴露会以性别依赖的方式影响小鼠的行为:例如,暴露于沉默的雄性小鼠,而不是雌性小鼠,相对于它们的原始对照,表现出对沉默的强烈偏好。与单纯的对照组相比,暴露在音乐或沉默环境中的小鼠听觉皮层的神经活动受到抑制。值得注意的是,雌性老鼠的神经反应和声音偏好之间存在明显的负相关,而雄性老鼠则没有。
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来源期刊
Cell reports
Cell reports CELL BIOLOGY-
CiteScore
13.80
自引率
1.10%
发文量
1305
审稿时长
77 days
期刊介绍: Cell Reports publishes high-quality research across the life sciences and focuses on new biological insight as its primary criterion for publication. The journal offers three primary article types: Reports, which are shorter single-point articles, research articles, which are longer and provide deeper mechanistic insights, and resources, which highlight significant technical advances or major informational datasets that contribute to biological advances. Reviews covering recent literature in emerging and active fields are also accepted. The Cell Reports Portfolio includes gold open-access journals that cover life, medical, and physical sciences, and its mission is to make cutting-edge research and methodologies available to a wide readership. The journal's professional in-house editors work closely with authors, reviewers, and the scientific advisory board, which consists of current and future leaders in their respective fields. The advisory board guides the scope, content, and quality of the journal, but editorial decisions are independently made by the in-house scientific editors of Cell Reports.
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