Advancing Sulfono Functionalization: Integrating Classic and Contemporary Approaches to Drive Innovation in Synthetic Chemistry

IF 2.7 4区化学 Q1 CHEMISTRY, ORGANIC

Asian Journal of Organic Chemistry Pub Date : 2025-10-01 DOI:10.1002/ajoc.202500456

Bhaskarjyoti Borah , Sushmita Banerjee , Bharat Kumar Allam

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Abstract

The growing significance of sulfone‐containing compounds in pharmaceuticals, agrochemicals, and materials science has driven interest in innovative sulfono functionalization strategies. Despite the progress, the diversity of emerging methods, from transition metal catalysis to photoredox and electrochemical approaches, has led to a fragmented understanding across disciplines. This review article aims to consolidate recent advancements, critically analyze current methodologies, and highlight trends shaping the future of sulfono chemistry. By offering a comprehensive overview of established and novel synthetic techniques, this review is a valuable resource for researchers, aiding in the rational design of sulfone‐based molecules and fostering the development of more sustainable, efficient, and selective functionalization protocols. Ultimately, it bridges gaps in literature, stimulates interdisciplinary collaboration, and identifies unexplored avenues for future research.

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推进磺胺功能化：整合经典和现代的方法来推动合成化学的创新

含砜化合物在制药、农用化学品和材料科学中的重要性日益增加，促使人们对创新的磺功能化策略产生了兴趣。尽管取得了进展，但新兴方法的多样性，从过渡金属催化到光氧化还原和电化学方法，导致了跨学科的碎片化理解。这篇综述文章旨在巩固最近的进展，批判性地分析当前的方法，并强调趋势塑造未来的磺化学。通过对现有和新型合成技术的全面概述，本综述为研究人员提供了宝贵的资源，有助于合理设计基于砜的分子，并促进更可持续，高效和选择性功能化方案的发展。最终，它弥合了文献中的空白，促进了跨学科的合作，并为未来的研究确定了尚未探索的途径。

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来源期刊

Asian Journal of Organic Chemistry CHEMISTRY, ORGANIC-

CiteScore

4.70

自引率

3.70%

发文量

372

期刊介绍： Organic chemistry is the fundamental science that stands at the heart of chemistry, biology, and materials science. Research in these areas is vigorous and truly international, with three major regions making almost equal contributions: America, Europe and Asia. Asia now has its own top international organic chemistry journal—the Asian Journal of Organic Chemistry (AsianJOC) The AsianJOC is designed to be a top-ranked international research journal and publishes primary research as well as critical secondary information from authors across the world. The journal covers organic chemistry in its entirety. Authors and readers come from academia, the chemical industry, and government laboratories.