Self-Disassembling Macroporous Metal–Organic Framework-Based Micromotors with Magnetically Controlled Motion for Sequential Drug Release (Small Methods 10/2025)

Abstract

Sequential Drug Release

MOF-based magnetic micromotors self-degrade to release two drugs in a controlled and sequential manner at the acidic cancer cells media. The magnetic propulsion of the micromotors facilitates targeted delivery to pre-designated locations, enabling interaction with cancer cells in the culture medium. This approach allows for controlled binding, transport, and membrane rupture toward future in-vivo treatment of tumors. More in article number 2500724, Sánchez, Escarpa, and co-workers.