Development of novel DALY-based indices for assessing productivity loss and resource allocation for liver cancer in the MENA region.

IF 2.5 2区医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Population Health Metrics Pub Date : 2025-10-17 DOI:10.1186/s12963-025-00423-8

Shekoofeh Sadat Momahhed, Arian Banaee, Atefehsadat Haghighathoseini, Abolfazl Zendehdel

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引用次数: 0

Abstract

Objective: To develop new DALY-based indices for measuring productivity loss, health system resilience, and resource allocation efficiency for liver cancer across eight MENA countries. These will be combined into the Integrated Health-Adjusted Productivity Index (IHAPI) to aid health policy development.

Setting: The final analysis utilized 289,067 data entries from a total of 394,944, including information from Egypt, Iran, Jordan, Kuwait, Turkey, Saudi Arabia, Oman, and the UAE from 2000 to 2021.

Design: This study adopted a cross-country approach, employing secondary data to develop six composite measures: the Health-Adjusted Productivity Loss Index (HAPLI), the Economic Vulnerability to Health Impact Index (EVHI), the Relative Resilience to Liver Cancer Loss Index (RLCL), the Resource Allocation Efficiency Index (RAEI), the Health System Response Index (HSRI), and the Sustainable Development Health Equity Index (SD-HEI). These measures were aggregated into the IHAPI score.

Results: The analysis revealed that the most significant factor influencing the IHAPI score was the EVHI (feature importance = 0.73). Egypt exhibited the highest growth in Disability-Adjusted Life Years (DALY), leading to substantial productivity loss (HAPLI), while Saudi Arabia and Jordan demonstrated greater resilience (as indicated by higher RLCL scores and less variability in the IHAPI). The UAE and Turkey reported strong HSRI and Productivity Performance Index (PPI) rates, suggesting better-coordinated preventive investments. Conversely, the highest variability in the indices was observed in Iran and Oman, particularly in the SD-HEI and Total Productivity Loss and Inequality Index (TPLTI), indicating unstable equity and trends. Kuwait exhibited moderate performance in burden and resource allocation indices.

Conclusion: This paper presents an integrative model for evaluating both economic and health system impacts of liver cancer in MENA countries. The IHAPI and its related indices provide valuable insights that can be implemented to enhance equity, efficiency, and resilience in health policy.

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开发基于dali的新型指数，用于评估中东和北非地区肝癌的生产力损失和资源分配。

目的：开发新的基于daly的指数，用于衡量八个中东和北非国家肝癌的生产力损失、卫生系统弹性和资源配置效率。这些指标将被纳入经健康调整后的综合生产力指数（IHAPI），以帮助制定卫生政策。背景：最终分析使用了总共394,944个数据条目中的289,067个数据条目，包括2000年至2021年来自埃及、伊朗、约旦、科威特、土耳其、沙特阿拉伯、阿曼和阿联酋的信息。设计：本研究采用跨国方法，利用二手数据制定了6个综合指标：健康调整生产力损失指数（HAPLI）、健康影响经济脆弱性指数（EVHI）、肝癌损失相对恢复指数（RLCL）、资源配置效率指数（RAEI）、卫生系统响应指数（HSRI）和可持续发展健康公平指数（SD-HEI）。这些措施被汇总成IHAPI得分。结果：分析显示影响IHAPI评分最显著的因素是EVHI（特征重要性= 0.73）。埃及的残疾调整生命年（DALY）增长最快，导致大量生产力损失（HAPLI），而沙特阿拉伯和约旦表现出更强的复原力（RLCL得分较高，IHAPI变化较小）。阿联酋和土耳其报告了强劲的HSRI和生产力绩效指数（PPI），表明预防性投资得到了更好的协调。相反，伊朗和阿曼的指数变化最大，特别是在SD-HEI和总生产力损失和不平等指数（TPLTI）中，表明不稳定的公平性和趋势。科威特在负担和资源分配指标上表现一般。结论：本文提出了一个综合模型，用于评估中东和北非国家肝癌对经济和卫生系统的影响。IHAPI及其相关指数提供了宝贵的见解，可用于加强卫生政策的公平性、效率和复原力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Population Health Metrics PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-

CiteScore

6.50

自引率

0.00%

发文量

审稿时长

29 weeks

期刊介绍： Population Health Metrics aims to advance the science of population health assessment, and welcomes papers relating to concepts, methods, ethics, applications, and summary measures of population health. The journal provides a unique platform for population health researchers to share their findings with the global community. We seek research that addresses the communication of population health measures and policy implications to stakeholders; this includes papers related to burden estimation and risk assessment, and research addressing population health across the full range of development. Population Health Metrics covers a broad range of topics encompassing health state measurement and valuation, summary measures of population health, descriptive epidemiology at the population level, burden of disease and injury analysis, disease and risk factor modeling for populations, and comparative assessment of risks to health at the population level. The journal is also interested in how to use and communicate indicators of population health to reduce disease burden, and the approaches for translating from indicators of population health to health-advancing actions. As a cross-cutting topic of importance, we are particularly interested in inequalities in population health and their measurement.