Matthew K Wun, Michael H Court, Nicolas F Villarino, Richard Malik
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引用次数: 0
Abstract
Over the past 20 years, injectable non-steroidal anti-inflammatory drugs (NSAIDs) have become widely adopted to provide routine analgesia to dogs and cats, including perioperatively. This is despite growing evidence associating their use with acute kidney injury, particularly in relation to the use of meloxicam in cats. In this Perspective, we summarise the evidence obtained from pharmacovigilance agencies and the veterinary literature, examine why proponents of injectable NSAIDs appear to discard this evidence, and discuss whether injectable NSAIDs are an obligatory component of multimodal analgesia. Finally, we offer alternative analgesic drug regimens and call for further research that could be undertaken before injectable NSAIDs can be used safely in dogs and cats.
期刊介绍:
Veterinary Anaesthesia and Analgesia is the official journal of the Association of Veterinary Anaesthetists, the American College of Veterinary Anesthesia and Analgesia and the European College of Veterinary Anaesthesia and Analgesia. Its purpose is the publication of original, peer reviewed articles covering all branches of anaesthesia and the relief of pain in animals. Articles concerned with the following subjects related to anaesthesia and analgesia are also welcome:
the basic sciences;
pathophysiology of disease as it relates to anaesthetic management
equipment
intensive care
chemical restraint of animals including laboratory animals, wildlife and exotic animals
welfare issues associated with pain and distress
education in veterinary anaesthesia and analgesia.
Review articles, special articles, and historical notes will also be published, along with editorials, case reports in the form of letters to the editor, and book reviews. There is also an active correspondence section.