Primary Bladder Neck Obstruction in Women: A Systematic Review.

IF 2.9 2区 医学 Q2 UROLOGY & NEPHROLOGY
Dora Jericevic Schwartz, Maxine Parkinson, Benjamin M Brucker
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引用次数: 0

Abstract

Purpose of review: To systematically evaluate and synthesize the existing literature on treatment outcomes for primary bladder neck obstruction (PBNO) in women, given the absence of prior systematic reviews focused on this population.

Recent findings: Current treatment options for PBNO in women include nonsurgical alpha-adrenergic receptor blockers (AB), surgical bladder neck incision (BNI), and investigational use of onabotulinumtoxinA injections (BTX-BN). Success rates for AB and BNI are approximately 50% and 75%, respectively, while BTX-BN appears to have lower efficacy. The existing studies on PBNO treatment in women are characterized by significant heterogeneity and a lack of high-quality evidence. Standardization is needed across multiple domains, including the definition of PBNO in women, the recommended diagnostic workup, and the establishment of criteria for treatment success and failure. Investigation of risk factors for treatment failure is also needed to better inform patient counseling and management.

女性原发性膀胱颈梗阻:一项系统综述。
综述的目的:在缺乏针对女性原发性膀胱颈梗阻(PBNO)的系统综述的情况下,系统地评价和综合现有的关于女性原发性膀胱颈梗阻治疗结果的文献。近期发现:目前女性PBNO的治疗方案包括非手术α -肾上腺素能受体阻滞剂(AB)、手术膀胱颈部切开(BNI)和实验性使用肉毒杆菌毒素a注射(BTX-BN)。AB和BNI的成功率分别约为50%和75%,而BTX-BN的疗效似乎较低。现有关于女性PBNO治疗的研究具有显著的异质性和缺乏高质量证据的特点。需要跨多个领域的标准化,包括妇女PBNO的定义、推荐的诊断检查以及治疗成功和失败标准的建立。还需要调查治疗失败的危险因素,以便更好地为患者咨询和管理提供信息。
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来源期刊
Current Urology Reports
Current Urology Reports UROLOGY & NEPHROLOGY-
CiteScore
4.60
自引率
3.80%
发文量
39
期刊介绍: This journal intends to review the most important, recently published findings in the field of urology. By providing clear, insightful, balanced contributions by international experts, the journal elucidates current and emerging approaches to the care and prevention of urologic diseases and conditions. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas, such as benign prostatic hyperplasia, erectile dysfunction, female urology, and kidney disease. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. An international Editorial Board reviews the annual table of contents, suggests articles of special interest to their country/region, and ensures that topics are current and include emerging research. Commentaries from well-known figures in the field are also provided.
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