Dora Jericevic Schwartz, Maxine Parkinson, Benjamin M Brucker
{"title":"Primary Bladder Neck Obstruction in Women: A Systematic Review.","authors":"Dora Jericevic Schwartz, Maxine Parkinson, Benjamin M Brucker","doi":"10.1007/s11934-025-01295-z","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose of review: </strong>To systematically evaluate and synthesize the existing literature on treatment outcomes for primary bladder neck obstruction (PBNO) in women, given the absence of prior systematic reviews focused on this population.</p><p><strong>Recent findings: </strong>Current treatment options for PBNO in women include nonsurgical alpha-adrenergic receptor blockers (AB), surgical bladder neck incision (BNI), and investigational use of onabotulinumtoxinA injections (BTX-BN). Success rates for AB and BNI are approximately 50% and 75%, respectively, while BTX-BN appears to have lower efficacy. The existing studies on PBNO treatment in women are characterized by significant heterogeneity and a lack of high-quality evidence. Standardization is needed across multiple domains, including the definition of PBNO in women, the recommended diagnostic workup, and the establishment of criteria for treatment success and failure. Investigation of risk factors for treatment failure is also needed to better inform patient counseling and management.</p>","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":"26 1","pages":"67"},"PeriodicalIF":2.9000,"publicationDate":"2025-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Urology Reports","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s11934-025-01295-z","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"UROLOGY & NEPHROLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Purpose of review: To systematically evaluate and synthesize the existing literature on treatment outcomes for primary bladder neck obstruction (PBNO) in women, given the absence of prior systematic reviews focused on this population.
Recent findings: Current treatment options for PBNO in women include nonsurgical alpha-adrenergic receptor blockers (AB), surgical bladder neck incision (BNI), and investigational use of onabotulinumtoxinA injections (BTX-BN). Success rates for AB and BNI are approximately 50% and 75%, respectively, while BTX-BN appears to have lower efficacy. The existing studies on PBNO treatment in women are characterized by significant heterogeneity and a lack of high-quality evidence. Standardization is needed across multiple domains, including the definition of PBNO in women, the recommended diagnostic workup, and the establishment of criteria for treatment success and failure. Investigation of risk factors for treatment failure is also needed to better inform patient counseling and management.
期刊介绍:
This journal intends to review the most important, recently published findings in the field of urology. By providing clear, insightful, balanced contributions by international experts, the journal elucidates current and emerging approaches to the care and prevention of urologic diseases and conditions.
We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas, such as benign prostatic hyperplasia, erectile dysfunction, female urology, and kidney disease. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. An international Editorial Board reviews the annual table of contents, suggests articles of special interest to their country/region, and ensures that topics are current and include emerging research. Commentaries from well-known figures in the field are also provided.