Benzodiazepine use in physicians: retrospective 5-year nationwide study in Taiwan.

IF 3.5 3区 医学 Q1 PSYCHIATRY
Wan-Ju Cheng, Yin-Chieh Chuang, Hsuan-Ching Wang, Hei-Tung Yip, Cheng-Li Lin, Cynthia Wei-Sheng Lee
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Abstract

Background: Benzodiazepine use among physicians is an important public health issue related to physicians' well-being and patient safety.

Aims: This study aimed to evaluate the patterns and correlates of benzodiazepine use in physicians by comparing the characteristics of heavy users with those of low-dose users.

Method: We identified 4844 physicians with a history of benzodiazepine use as the benzodiazepine cohort from 32 080 physicians from the population-based Taiwan National Health Insurance Research Database from 2014 to 2020. Benzodiazepine users were divided into low-dose, intermediate and heavy users based on their yearly equivalent dosage of <20, 20-150 and >150 defined daily dose (DDD) per year, respectively. Differences in demographic characteristics and specialities between the benzodiazepine and control cohorts were compared via univariate and multivariate logistic regression models. A generalised estimating equation was used to investigate the relationship between benzodiazepine use and comorbidities.

Results: Among all of the physicians, 15.1% used benzodiazepine. Male physicians were more likely to use benzodiazepines and become heavy users. Older age, sleep disorders and depression were significantly associated with heavy benzodiazepine use. Regarding physician specialities, the highest prevalence of benzodiazepine use was observed in otorhinolaryngology (19.8%), followed by family medicine (19.1%). Odds of benzodiazepine use were 2.20 and 2.90 times greater in physicians with sleep disorders and depression, respectively.

Conclusions: Comorbidities of depression and sleep disorders are associated with increased probability of benzodiazepine use. Providing stress-coping strategies and appropriate treatment for mental disorders is recommended to support the overall well-being of physicians.

医师使用苯二氮卓类药物:台湾5年全国性回顾性研究。
背景:苯二氮卓类药物在医生中的使用是一个重要的公共卫生问题,关系到医生的福祉和患者的安全。目的:本研究旨在通过比较重度使用者和低剂量使用者的特点来评估苯二氮卓类药物在医生中的使用模式和相关因素。方法:我们从2014年至2020年以人口为基础的台湾全民健康保险研究数据库的32,080名医生中,筛选出4844名有苯二氮卓类药物使用史的医生作为苯二氮卓类药物队列。根据每年150定义日剂量(DDD)的年等效剂量,将苯二氮卓类药物使用者分别分为低剂量、中剂量和重度使用者。通过单变量和多变量logistic回归模型比较苯二氮卓类药物组和对照组在人口统计学特征和专业方面的差异。使用广义估计方程来研究苯二氮卓类药物使用与合并症之间的关系。结果:15.1%的医生使用苯二氮卓类药物。男性医生更有可能使用苯二氮卓类药物并成为重度使用者。年龄较大、睡眠障碍和抑郁症与大量使用苯二氮卓类药物显著相关。在医生专业方面,苯二氮卓类药物使用率最高的是耳鼻喉科(19.8%),其次是家庭医学(19.1%)。患有睡眠障碍和抑郁症的医生使用苯二氮卓类药物的几率分别是前者的2.20倍和2.90倍。结论:抑郁症和睡眠障碍的合并症与苯二氮卓类药物使用的可能性增加有关。建议提供压力应对策略和适当的精神障碍治疗,以支持医生的整体福祉。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
BJPsych Open
BJPsych Open Medicine-Psychiatry and Mental Health
CiteScore
6.30
自引率
3.70%
发文量
610
审稿时长
16 weeks
期刊介绍: Announcing the launch of BJPsych Open, an exciting new open access online journal for the publication of all methodologically sound research in all fields of psychiatry and disciplines related to mental health. BJPsych Open will maintain the highest scientific, peer review, and ethical standards of the BJPsych, ensure rapid publication for authors whilst sharing research with no cost to the reader in the spirit of maximising dissemination and public engagement. Cascade submission from BJPsych to BJPsych Open is a new option for authors whose first priority is rapid online publication with the prestigious BJPsych brand. Authors will also retain copyright to their works under a creative commons license.
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