Leptospirosis in the United Kingdom: a decade of experience from a large regional hospital

IF 4.7 3区医学 Q1 INFECTIOUS DISEASES

Travel Medicine and Infectious Disease Pub Date : 2025-10-13 DOI:10.1016/j.tmaid.2025.102920

Andrew Taylor , Paul N. Newton , Ivo Elliott

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引用次数: 0

Abstract

Background

Leptospirosis is one of the most common bacterial zoonoses worldwide, with a broad spectrum of illness from mild and self-resolving to multi-organ failure and death. There have been few reports of the epidemiology, clinical features and outcomes of the disease in the United Kingdom.

Methods

We present experience of 29 patients with confirmed leptospirosis from 924 tested patients over a 10-year period at a large tertiary hospital in the UK.

Results

All patients reported a fever and eit travel overseas in the 6 weeks prior to illness, or documented exposure to water or animals in the UK. Acute kidney injury occurred in 18/29 (62 %), 6 patients (20 %) required admission to the intensive care unit and 1 died. There were no recorded acquired UK cases during winter when water temperatures are usually below 10 °C.

Conclusions

Epidemiological awareness and documented exposure history may increase the proportion of positive tests and offer potential laboratory cost savings.

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英国钩端螺旋体病：一家大型地区医院的十年经验。

背景：钩端螺旋体病是世界范围内最常见的细菌性人畜共患病之一，疾病范围广泛，从轻度和自愈到多器官衰竭和死亡。在英国，关于该病的流行病学、临床特征和预后的报道很少。方法：我们目前的经验29名患者确诊钩端螺旋体病从924检测患者超过10年期间在英国一家大型三级医院。结果：所有患者报告在发病前6周内发烧并出国旅行，或记录在英国接触水或动物。急性肾损伤18/29例（62%），6例（20%）需入院重症监护，1例死亡。在水温通常低于10°C的冬季，没有记录在案的英国病例。结论：流行病学意识和有记录的暴露史可能会增加阳性检测的比例，并可能节省实验室费用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Travel Medicine and Infectious Disease PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-INFECTIOUS DISEASES

CiteScore

19.40

自引率

1.70%

发文量

211

审稿时长

49 days

期刊介绍： Travel Medicine and Infectious Disease Publication Scope: Publishes original papers, reviews, and consensus papers Primary theme: infectious disease in the context of travel medicine Focus Areas: Epidemiology and surveillance of travel-related illness Prevention and treatment of travel-associated infections Malaria prevention and treatment Travellers' diarrhoea Infections associated with mass gatherings Migration-related infections Vaccines and vaccine-preventable disease Global policy/regulations for disease prevention and control Practical clinical issues for travel and tropical medicine practitioners Coverage: Addresses areas of controversy and debate in travel medicine Aims to inform guidelines and policy pertinent to travel medicine and the prevention of infectious disease Publication Features: Offers a fast peer-review process Provides early online publication of accepted manuscripts Aims to publish cutting-edge papers