Wearable biomolecular sensing nanotechnologies in chronic disease management.

IF 34.9 1区材料科学 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY

Nature nanotechnology Pub Date : 2025-10-15 DOI:10.1038/s41565-025-02010-2

Jiaobing Tu, Connor D Flynn, Jeonghee Yeom, Zhenwei Wu, Shana O Kelley, Wei Gao

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引用次数: 0

Abstract

Over the past decade, consumer wearable sensors have become increasingly ubiquitous in health monitoring, enabling the widespread tracking of key biophysical parameters. The transition towards next-generation body-interfaced biomolecular sensing technologies, fuelled by the integration of reagentless sensing strategies with advanced nanomaterials, marks the next substantial leap forward. These innovations enable unobtrusive, multimodal monitoring of both physiological parameters and biochemical disease markers in real time. This Review examines the current generation of body-interfaced biomolecular sensing technologies, with a particular emphasis on materials innovation and nanotechnological advancements, and discusses their pivotal role in chronic disease monitoring. The discussion extends to the challenges and prospects in this rapidly evolving field, highlighting the potential for materials-focused approaches to transform the landscape of chronic disease monitoring and management with body-interfaced bioelectronics. By harnessing the power of materials and nanotechnological innovations, these biomolecular sensing technologies promise to enhance diagnostic capabilities and foster a more proactive, personalized approach to combating these diseases.

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可穿戴生物分子传感纳米技术在慢性疾病管理中的应用。

在过去的十年中，消费者可穿戴传感器在健康监测中变得越来越普遍，使关键生物物理参数的广泛跟踪成为可能。在无试剂传感策略与先进纳米材料相结合的推动下，向下一代身体界面生物分子传感技术的过渡标志着下一个实质性的飞跃。这些创新使生理参数和生化疾病标志物的实时监测不引人注目，多模式。本文综述了当前一代的身体界面生物分子传感技术，特别强调材料创新和纳米技术的进步，并讨论了它们在慢性疾病监测中的关键作用。讨论扩展到这个快速发展领域的挑战和前景，强调了以材料为中心的方法的潜力，以改变慢性疾病监测和管理的景观与身体接口生物电子学。通过利用材料和纳米技术创新的力量，这些生物分子传感技术有望提高诊断能力，并培养一种更主动、更个性化的方法来对抗这些疾病。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nature nanotechnology 工程技术-材料科学：综合

CiteScore

59.70

自引率

0.80%

发文量

196

审稿时长

4-8 weeks

期刊介绍： Nature Nanotechnology is a prestigious journal that publishes high-quality papers in various areas of nanoscience and nanotechnology. The journal focuses on the design, characterization, and production of structures, devices, and systems that manipulate and control materials at atomic, molecular, and macromolecular scales. It encompasses both bottom-up and top-down approaches, as well as their combinations. Furthermore, Nature Nanotechnology fosters the exchange of ideas among researchers from diverse disciplines such as chemistry, physics, material science, biomedical research, engineering, and more. It promotes collaboration at the forefront of this multidisciplinary field. The journal covers a wide range of topics, from fundamental research in physics, chemistry, and biology, including computational work and simulations, to the development of innovative devices and technologies for various industrial sectors such as information technology, medicine, manufacturing, high-performance materials, energy, and environmental technologies. It includes coverage of organic, inorganic, and hybrid materials.