Electroactive TiO₂–Cu nanotube platform with synergistic charge modulation and Cu2+ release for marine antifouling

IF 4.9 2区化学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Bioelectrochemistry Pub Date : 2026-03-01 Epub Date: 2025-10-11 DOI:10.1016/j.bioelechem.2025.109135

Yuqiao Dong , Yuxuan Xu , Jinke Yin , Qianwen Jin , Guangzhou Liu

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引用次数: 0

Abstract

Biological damage remains a critical limiting factor that hinders the application of highly biocompatible titanium alloys in marine engineering. Exploiting the delicate electrostatic interactions at the interface between organisms and nanomaterials is of vital importance. In this study, an external direct current was applied to copper-coated capacitive TiO₂ nanotubes (TNT-Cu) to evaluate the antifouling effect on sessile biofilms and planktonic bacteria, and to elucidate the underlying mechanisms. The heterostructure exhibited high specific capacitance and superior antifouling performance. Upon electrochemical charge-discharge, TNT-Cu achieved 98.3 ± 0.9 % adhesion inhibition and 96.0 ± 2.0 % algicidal activity against Phaeodactylum tricornutum. The charged TNT-Cu achieved synergistic antifouling through surface charge–induced electrostatic sterilization and controlled Cu²⁺ release. Physiologically, the electrical interaction combined with Cu²⁺ significantly disrupted algal electron transport, induced reactive oxygen species (ROS) accumulation, and caused membrane rupture. This work provides a promising, durable, and eco-friendly antifouling strategy for marine applications of titanium-based materials.

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具有协同电荷调制和Cu2+释放的电活性tio2 -Cu纳米管平台用于船舶防污。

生物损伤是制约高生物相容性钛合金在海洋工程中应用的重要因素。利用生物与纳米材料界面上微妙的静电相互作用是至关重要的。本研究通过对铜包覆的电容性纳米管（TNT-Cu）施加外部直流电，考察其对固定式生物膜和浮游细菌的防污作用，并探讨其机制。该异质结构具有较高的比电容和优异的防污性能。电化学充放电后，TNT-Cu对三角褐指藻的粘附抑制率为98.3%±0.9%，杀藻活性为96.0%±2.0%。带电荷的TNT-Cu通过表面电荷诱导的静电灭菌和控制Cu2+释放来实现协同防污。生理上，电相互作用与Cu2+的结合显著破坏了藻类的电子传递，诱导活性氧（ROS）积累，并导致膜破裂。这项工作为钛基材料的海洋应用提供了一种有前途的、耐用的、环保的防污策略。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Bioelectrochemistry 生物-电化学

CiteScore

9.10

自引率

6.00%

发文量

238

审稿时长

38 days

期刊介绍： An International Journal Devoted to Electrochemical Aspects of Biology and Biological Aspects of Electrochemistry Bioelectrochemistry is an international journal devoted to electrochemical principles in biology and biological aspects of electrochemistry. It publishes experimental and theoretical papers dealing with the electrochemical aspects of: • Electrified interfaces (electric double layers, adsorption, electron transfer, protein electrochemistry, basic principles of biosensors, biosensor interfaces and bio-nanosensor design and construction. • Electric and magnetic field effects (field-dependent processes, field interactions with molecules, intramolecular field effects, sensory systems for electric and magnetic fields, molecular and cellular mechanisms) • Bioenergetics and signal transduction (energy conversion, photosynthetic and visual membranes) • Biomembranes and model membranes (thermodynamics and mechanics, membrane transport, electroporation, fusion and insertion) • Electrochemical applications in medicine and biotechnology (drug delivery and gene transfer to cells and tissues, iontophoresis, skin electroporation, injury and repair). • Organization and use of arrays in-vitro and in-vivo, including as part of feedback control. • Electrochemical interrogation of biofilms as generated by microorganisms and tissue reaction associated with medical implants.