Diagnostic Value of Contrast-Enhanced Ultrasound in Detecting Abdominal Metastases From Gastrointestinal Stromal Tumors.

IF 1.4 4区医学 Q3 ACOUSTICS

Journal of Clinical Ultrasound Pub Date : 2025-10-14 DOI:10.1002/jcu.70114

Hong Yue, Xuemei He, Jing Sun, Jiangyan Yin, Chongqing Cheng, Tiantian Wang

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引用次数: 0

Abstract

Objective: To assess the diagnostic performance of contrast-enhanced ultrasound (CEUS) for detecting abdominal metastases in patients with gastrointestinal stromal tumors (GISTs), with a comparison to conventional ultrasonography (US) and contrast-enhanced computed tomography (CE-CT).

Methods: This retrospective study enrolled 53 patients with pathologically confirmed abdominal metastases from gastrointestinal stromal tumors (GISTs), who underwent US, CEUS, and CE-CT examinations at our institution between January 2022 and January 2025. The diagnostic performance of CEUS was systematically evaluated and compared with US and CE-CT according to pathological diagnostic criteria.

Results: CEUS showed significantly higher sensitivity than US (88.68% vs. 45.28%; p < 0.05). Notably, CEUS achieved comparable performance to CE-CT (sensitivity: 88.68% vs. 94.34%; p > 0.05). No statistically significant differences were observed between CEUS and CE-CT in lesion perfusion characteristics, including enhancement pattern (p > 0.05), intensity (p > 0.05), and homogeneity (p > 0.05).

Conclusions: CEUS demonstrates superior diagnostic performance to US in detecting abdominal metastases from GISTs, with efficacy comparable to CE-CT. Given its radiation-free nature and procedural simplicity, CEUS represents a valuable imaging modality for the clinical assessment of GIST metastases.

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超声造影对胃肠道间质瘤腹腔转移的诊断价值。

目的：评价对比增强超声（CEUS）对胃肠道间质瘤（gist）患者腹部转移的诊断价值，并与常规超声（US）和对比增强ct （CE-CT）进行比较。方法：本回顾性研究纳入了53例病理证实的胃肠道间质瘤（gist）腹部转移患者，这些患者于2022年1月至2025年1月在我院接受了US、CEUS和CE-CT检查。根据病理诊断标准，系统评价超声造影的诊断效能，并与超声及CE-CT进行比较。结果：CEUS的敏感性显著高于US （88.68% vs. 45.28%; p 0.05）。CEUS与CE-CT在病灶灌注特征，包括增强模式（p > 0.05）、强度（p > 0.05）、均匀性（p > 0.05）等方面均无统计学差异。结论：超声造影对胃肠道间质瘤腹腔转移的诊断效果优于超声，其诊断效果与CE-CT相当。鉴于其无辐射的性质和操作简单，超声造影是临床评估GIST转移的一种有价值的成像方式。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Clinical Ultrasound 医学-核医学

CiteScore

1.90

自引率

0.00%

发文量

248

审稿时长

6 months

期刊介绍： The Journal of Clinical Ultrasound (JCU) is an international journal dedicated to the worldwide dissemination of scientific information on diagnostic and therapeutic applications of medical sonography. The scope of the journal includes--but is not limited to--the following areas: sonography of the gastrointestinal tract, genitourinary tract, vascular system, nervous system, head and neck, chest, breast, musculoskeletal system, and other superficial structures; Doppler applications; obstetric and pediatric applications; and interventional sonography. Studies comparing sonography with other imaging modalities are encouraged, as are studies evaluating the economic impact of sonography. Also within the journal''s scope are innovations and improvements in instrumentation and examination techniques and the use of contrast agents. JCU publishes original research articles, case reports, pictorial essays, technical notes, and letters to the editor. The journal is also dedicated to being an educational resource for its readers, through the publication of review articles and various scientific contributions from members of the editorial board and other world-renowned experts in sonography.