Gastric Morphology During Gastroscopy Associated with Helicobacter pylori Infection.

IF 1.9 2区农林科学 Q3 FOOD SCIENCE & TECHNOLOGY

Foodborne pathogens and disease Pub Date : 2025-10-15 DOI:10.1177/15353141251388852

Mo Qu, Chendi Wang

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引用次数: 0

Abstract

As a Gram-negative, microaerophilic bacterium, Helicobacter pylori (H. pylori) colonizes and thrives in the gastric mucosa. To enable early detection and treatment of H. pylori infection through exploring the clinical value of white light gastroscope endoscopic features in diagnosing H. pylori. A retrospective analysis was conducted on 968 patients who underwent routine gastroscopy over a 2-year period (March 1st, 2021-March 1st, 2023). A significant association was observed between H. pylori infection and age (p < 0.001), family history of H. pylori infection (p < 0.001), and gastric symptoms (p < 0.001). White light gastroscope findings demonstrated that diffuse erythema (p < 0.001), spotted redness (p < 0.001), mucosal swelling (p < 0.001), elongated and enlarged folds (p < 0.001), digestive tract ulcers (p < 0.001), proliferative polyps (p = 0.018), and erosions with depression (p < 0.001) were more frequent in H. pylori-infected individuals. Conversely, old bleeding spots (p = 0.003), gastric fundic glandular polyps (p = 0.048), and regular arrangement of collecting venules (RAC) (p < 0.001) were less common in H. pylori-infected patients. Diffuse erythema (odds ratio [OR] = 3.84, p = 0.002), spotted redness (OR = 2.63, p = 0.008), mucosal swelling (OR = 1.97, p = 0.007), elongated and enlarged folds (OR = 2.15, p = 0.015), digestive tract ulcers (OR = 1.49, p = 0.036), and erosions with depression (OR = 1.86, p = 0.022) were identified as independent risk factors for H. pylori infection, while the RAC served as a protective factor.

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幽门螺杆菌感染与胃镜检查时胃形态的关系。

作为一种革兰氏阴性的微嗜气细菌，幽门螺杆菌（H. pylori）在胃粘膜中定植并繁殖。通过探讨白光胃镜内镜特征在诊断幽门螺旋杆菌中的临床价值，早期发现和治疗幽门螺旋杆菌感染。回顾性分析968例2年内（2021年3月1日- 2023年3月1日）行常规胃镜检查的患者。幽门螺杆菌感染与年龄（p < 0.001）、幽门螺杆菌感染家族史（p < 0.001）和胃部症状（p < 0.001）有显著相关性。白光胃镜检查结果显示，弥漫性红斑（p < 0.001）、斑点性红肿（p < 0.001）、粘膜肿胀（p < 0.001）、褶皱拉长和扩大（p < 0.001）、消化道溃疡（p < 0.001）、增殖性息肉（p = 0.018）和糜烂伴凹陷（p < 0.001）在幽门螺杆菌感染者中更为常见。相反，幽门螺杆菌感染患者的老年性出血点（p = 0.003）、胃底腺息肉（p = 0.048）和收集小静脉整齐排列（RAC）（p < 0.001）较少。弥漫性红斑（优势比[OR] = 3.84, p = 0.002）、红斑性发红（优势比[OR] = 2.63, p = 0.008）、粘膜肿胀（优势比[OR] = 1.97, p = 0.007）、褶皱延长和扩大（优势比[OR] = 2.15, p = 0.015）、消化道溃疡（优势比[OR] = 1.49, p = 0.036）、糜烂伴凹陷（优势比[OR] = 1.86, p = 0.022）是幽门螺杆菌感染的独立危险因素，而RAC是保护因素。

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来源期刊

Foodborne pathogens and disease 医学-食品科技

CiteScore

5.30

自引率

3.60%

发文量

审稿时长

1 months

期刊介绍： Foodborne Pathogens and Disease is one of the most inclusive scientific publications on the many disciplines that contribute to food safety. Spanning an array of issues from "farm-to-fork," the Journal bridges the gap between science and policy to reduce the burden of foodborne illness worldwide. Foodborne Pathogens and Disease coverage includes: Agroterrorism Safety of organically grown and genetically modified foods Emerging pathogens Emergence of drug resistance Methods and technology for rapid and accurate detection Strategies to destroy or control foodborne pathogens Novel strategies for the prevention and control of plant and animal diseases that impact food safety Biosecurity issues and the implications of new regulatory guidelines Impact of changing lifestyles and consumer demands on food safety.