Nuclear medicine in hematology: Bridging diagnostics and therapy

IF 1.3 4区 医学 Q4 PHYSIOLOGY
Julius Jungnitsch, Kirsten Korsholm, Fazila Asmar, Søren Møller
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引用次数: 0

Abstract

The investigation and therapeutic trials of hematological and hemato-oncological diseases using nuclear medicine methods dates back to the 1930s. At that time, 32P was used as the isotope for various experimental procedures. Over the years, a wide variety of isotopes and techniques have been developed, some of which have established themselves as the gold standard in certain clinical indications, such as in the management of patients with lymphoma. Other nuclear medicine procedures are used as complementary techniques in more specific clinical scenarios. In recent years, the concept of theranostics has gained popularity in nuclear medicine. Radioendotherapies have been developed and some of them have already been FDA approved. Their promising results could potentially have a major impact on the treatment of patients with hemato-oncologic diseases. In this article we review some of the contemporary techniques used in nuclear medicine and recent developments of clinical indications in the field of hematology and oncology.

Abstract Image

血液学中的核医学:连接诊断和治疗。
利用核医学方法对血液学和血液肿瘤学疾病的研究和治疗试验可以追溯到20世纪30年代。当时,32P被用作各种实验程序的同位素。多年来,已经开发了各种各样的同位素和技术,其中一些已成为某些临床适应症的金标准,例如淋巴瘤患者的管理。其他核医学程序在更具体的临床情况下用作补充技术。近年来,治疗学的概念在核医学中得到了普及。放射疗法已经被开发出来,其中一些已经获得了FDA的批准。他们有希望的结果可能会对血液肿瘤疾病患者的治疗产生重大影响。在这篇文章中,我们回顾了一些用于核医学的当代技术和血液学和肿瘤学领域临床适应症的最新发展。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
3.40
自引率
5.60%
发文量
62
审稿时长
6-12 weeks
期刊介绍: Clinical Physiology and Functional Imaging publishes reports on clinical and experimental research pertinent to human physiology in health and disease. The scope of the Journal is very broad, covering all aspects of the regulatory system in the cardiovascular, renal and pulmonary systems with special emphasis on methodological aspects. The focus for the journal is, however, work that has potential clinical relevance. The Journal also features review articles on recent front-line research within these fields of interest. Covered by the major abstracting services including Current Contents and Science Citation Index, Clinical Physiology and Functional Imaging plays an important role in providing effective and productive communication among clinical physiologists world-wide.
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