{"title":"A review of molecular probes for nickel(II) ion sensing.","authors":"Sefiu Olalekan Olaleye","doi":"10.1039/d5ob01388g","DOIUrl":null,"url":null,"abstract":"<p><p>Water contamination by nickel poses serious risks to human health and ecosystems, underscoring the need for simple and effective sensor-based detection methods. This critical review covers research reported between 2006 and 2024 and explores the relationship between molecular design, structural motifs, and the performance of colorimetric and fluorescent chemosensors for nickel(II) ions. The analysis classifies sensors into categories-including rhodamine, fluorescein, Schiff base, naphthyridine, azo, polymer, imidazole, nanoparticle-based, quinoline, coumarin, and calixarene systems-to elucidate structure-property relationships. Complementing this, a bibliometric analysis of the research landscape reveals a notably lower publication output for nickel sensors compared to those for other metal ions, identifies 'chemosensor' as the most frequent keyword, and highlights India's leading role in co-authorship networks. This review provides valuable insights to guide future research, emphasizing the need to overcome key challenges such as reliance on organic solvents and to advance the development of practical and field-deployable nickel-sensing technologies.</p>","PeriodicalId":96,"journal":{"name":"Organic & Biomolecular Chemistry","volume":" ","pages":""},"PeriodicalIF":2.7000,"publicationDate":"2025-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Organic & Biomolecular Chemistry","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1039/d5ob01388g","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
引用次数: 0
Abstract
Water contamination by nickel poses serious risks to human health and ecosystems, underscoring the need for simple and effective sensor-based detection methods. This critical review covers research reported between 2006 and 2024 and explores the relationship between molecular design, structural motifs, and the performance of colorimetric and fluorescent chemosensors for nickel(II) ions. The analysis classifies sensors into categories-including rhodamine, fluorescein, Schiff base, naphthyridine, azo, polymer, imidazole, nanoparticle-based, quinoline, coumarin, and calixarene systems-to elucidate structure-property relationships. Complementing this, a bibliometric analysis of the research landscape reveals a notably lower publication output for nickel sensors compared to those for other metal ions, identifies 'chemosensor' as the most frequent keyword, and highlights India's leading role in co-authorship networks. This review provides valuable insights to guide future research, emphasizing the need to overcome key challenges such as reliance on organic solvents and to advance the development of practical and field-deployable nickel-sensing technologies.
期刊介绍:
Organic & Biomolecular Chemistry is an international journal using integrated research in chemistry-organic chemistry. Founded in 2003 by the Royal Society of Chemistry, the journal is published in Semimonthly issues and has been indexed by SCIE, a leading international database. The journal focuses on the key research and cutting-edge progress in the field of chemistry-organic chemistry, publishes and reports the research results in this field in a timely manner, and is committed to becoming a window and platform for rapid academic exchanges among peers in this field. The journal's impact factor in 2023 is 2.9, and its CiteScore is 5.5.