Comparison of coronary artery calcium scores between patients with and without type 2 diabetes.

Q2 Medicine
Mirza Babić, Zarina Babić Jušić, Sabina Prevljak, Fuad Zukić, Minela Bećirović, Amir Bećirović, Admir Abdić, Emir Bećirović
{"title":"Comparison of coronary artery calcium scores between patients with and without type 2 diabetes.","authors":"Mirza Babić, Zarina Babić Jušić, Sabina Prevljak, Fuad Zukić, Minela Bećirović, Amir Bećirović, Admir Abdić, Emir Bećirović","doi":"10.17392/1972-22-02","DOIUrl":null,"url":null,"abstract":"<p><p>Aim This study compared the extent of coronary artery calcification in patients with and without type 2 diabetes mellitus (T2DM) using Coronary Computed Tomography Angiography (CCTA). Methods This retrospective, observational cohort study included 107 patients who underwent CCTA at the Clinical Centre of the University of Sarajevo between July and December 2024. Patients were divided into two groups: those with T2DM (n=51) and those without T2DM (n=56). Laboratory parameters, demographic data, and calcium scores were analysed. The calcium score was categorised into six groups based on cardiovascular risk and the comparison was made using appropriate statistical analysis. Results Patients with T2DM had significantly higher calcium scores than non-diabetic patients (p=0.0001). In the T2DM group, 35.3% of patients had a calcium score &gt;400, indicating high cardiovascular risk. Patients without diabetes were more frequently classified into lower-risk categories (p=0.0001). A significant correlation was found between calcium score and age (r=0.442, p=0.001) and gender (r=-0.218, p=0.024), with men having higher calcium scores. Additionally, total cholesterol, LDL, and uric acid levels were significantly higher in diabetic patients (p=0.005; p=0.025; p=0.03, respectively). Conclusion This study confirms a strong association between T2DM and increased coronary artery calcification. Age and male gender are significant predictors of higher calcium scores. Further research is needed to explore these relationships, particularly within the Bosnian population. Keywords Coronary angiography, coronary artery calcification, coronary disease, diabetes mellitus type 2.</p>","PeriodicalId":51129,"journal":{"name":"Medicinski Glasnik","volume":"22 2","pages":"201-206"},"PeriodicalIF":0.0000,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medicinski Glasnik","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.17392/1972-22-02","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0

Abstract

Aim This study compared the extent of coronary artery calcification in patients with and without type 2 diabetes mellitus (T2DM) using Coronary Computed Tomography Angiography (CCTA). Methods This retrospective, observational cohort study included 107 patients who underwent CCTA at the Clinical Centre of the University of Sarajevo between July and December 2024. Patients were divided into two groups: those with T2DM (n=51) and those without T2DM (n=56). Laboratory parameters, demographic data, and calcium scores were analysed. The calcium score was categorised into six groups based on cardiovascular risk and the comparison was made using appropriate statistical analysis. Results Patients with T2DM had significantly higher calcium scores than non-diabetic patients (p=0.0001). In the T2DM group, 35.3% of patients had a calcium score >400, indicating high cardiovascular risk. Patients without diabetes were more frequently classified into lower-risk categories (p=0.0001). A significant correlation was found between calcium score and age (r=0.442, p=0.001) and gender (r=-0.218, p=0.024), with men having higher calcium scores. Additionally, total cholesterol, LDL, and uric acid levels were significantly higher in diabetic patients (p=0.005; p=0.025; p=0.03, respectively). Conclusion This study confirms a strong association between T2DM and increased coronary artery calcification. Age and male gender are significant predictors of higher calcium scores. Further research is needed to explore these relationships, particularly within the Bosnian population. Keywords Coronary angiography, coronary artery calcification, coronary disease, diabetes mellitus type 2.

2型糖尿病患者与非2型糖尿病患者冠状动脉钙评分的比较。
目的应用冠状动脉ct血管造影(CCTA)比较2型糖尿病(T2DM)患者与非T2DM患者冠状动脉钙化程度。方法:这项回顾性、观察性队列研究纳入了2024年7月至12月在萨拉热窝大学临床中心接受CCTA治疗的107例患者。患者分为两组:T2DM组(n=51)和非T2DM组(n=56)。分析实验室参数、人口统计数据和钙评分。根据心血管风险将钙评分分为六组,并进行适当的统计分析比较。结果T2DM患者的钙评分明显高于非糖尿病患者(p=0.0001)。在T2DM组中,35.3%的患者钙评分为400,表明心血管风险高。无糖尿病患者更常被归为低危组(p=0.0001)。钙评分与年龄(r=0.442, p=0.001)和性别(r=-0.218, p=0.024)有显著相关性,男性的钙评分较高。此外,糖尿病患者的总胆固醇、低密度脂蛋白和尿酸水平显著较高(p=0.005; p=0.025; p=0.03)。结论:本研究证实了T2DM与冠状动脉钙化增加之间的密切联系。年龄和男性性别是高钙评分的重要预测因素。需要进一步研究以探讨这些关系,特别是在波斯尼亚人口内部的关系。冠状动脉造影,冠状动脉钙化,冠心病,2型糖尿病
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Medicinski Glasnik
Medicinski Glasnik 医学-医学:内科
CiteScore
2.30
自引率
0.00%
发文量
0
审稿时长
6-12 weeks
期刊介绍: Medicinski Glasnik (MG) is the official publication (two times per year) of the Medical Association of Zenica-Doboj Canton. Manuscripts that present of original basic and applied research from all fields of medicine (general and clinical practice, and basic medical sciences) are invited.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信