Resident memory T cells call the shots in tissue immunity

IF 26.3 1区医学 Q1 IMMUNOLOGY

Immunity Pub Date : 2025-10-14 DOI:10.1016/j.immuni.2025.09.017

Sigrun Stulz, Georg Gasteiger

引用次数: 0

Abstract

Vaccines that induce immunity in tissues are urgently needed. In this issue of Immunity, Joag et al. demonstrate that systemic vaccination of primates induces tissue-resident CD8⁺ T cells in numerous organs that can activate antiviral responses by stromal, parenchymal, and immune cells.

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常驻记忆T细胞在组织免疫中发号施令

迫切需要在组织中诱导免疫的疫苗。在本期《免疫》杂志中，Joag等人证明，灵长类动物的全身疫苗接种可诱导许多器官中的组织驻留CD8+ T细胞，这些细胞可激活基质细胞、实质细胞和免疫细胞的抗病毒反应。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Immunity 医学-免疫学

CiteScore

49.40

自引率

2.20%

发文量

205

审稿时长

6 months

期刊介绍： Immunity is a publication that focuses on publishing significant advancements in research related to immunology. We encourage the submission of studies that offer groundbreaking immunological discoveries, whether at the molecular, cellular, or whole organism level. Topics of interest encompass a wide range, such as cancer, infectious diseases, neuroimmunology, autoimmune diseases, allergies, mucosal immunity, metabolic diseases, and homeostasis.