Nano vesicular approaches for the treatment of skin cancer.

Abstract

Skin cancer is increasing as a global health issue, with rising cases particularly in Caucasian populations. It is the most common cause of decreased quality of life worldwide. There are an estimated 1.5 million new cases each year. The conventional chemotherapy treatment is challenging and often ineffective. These problems can be overcome by the use of lipid nanoparticles and may allow for early detection and monitoring of neoplastic changes, and determine the effectiveness of the treatment. The lipid nanoparticle is significant in delivery systems due to its non-invasive and targeted delivery system is based on the type of active drug. Due to its ability to penetrate deep into the layers of the skin, skin delivery systems are capable of delivering drugs to target cells in a protected manner. Research over the previous decade on carriers of active substances indicates that drugs can be delivered more accurately to the tumor site, resulting in higher therapeutic efficacy. This article describes the application of liposomes, niosomes, ethosomes, transethosomes, transferosomes, invasomes, metal nanoparticles, and polymer nanoparticles in existing therapies. This review aimed to examine the properties and applications of nano lipid carriers used in the treatment and prevention of numerous types of skin cancer.