AIE Ir(III) complex conjugated with biotin as a photosensitizer for enhanced photodynamic anticancer therapy.

IF 4.2 2区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Chemical Communications Pub Date : 2025-10-13 DOI:10.1039/d5cc04806k

Zihan Wu,Runlin Wang,Chunguang Shi,Dongxia Zhu,Martin R Bryce

引用次数: 0

Abstract

The first aggregation induced emission (AIE) Ir(III) complex bearing a biotin-functionalized ligand, Ir-Bio, is reported. Ir-Bio generates type I and type II reactive oxygen species and has an excellent photodynamic therapy effect in cancer cells.

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AIE Ir（III）配合物与生物素结合作为光敏剂用于增强光动力抗癌治疗。

报道了第一个带有生物素功能化配体Ir- bio的聚集诱导发射（AIE） Ir（III）配合物。Ir-Bio产生I型和II型活性氧，对癌细胞具有良好的光动力治疗作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Chemical Communications 化学-化学综合

CiteScore

8.60

自引率

4.10%

发文量

2705

审稿时长

1.4 months

期刊介绍： ChemComm (Chemical Communications) is renowned as the fastest publisher of articles providing information on new avenues of research, drawn from all the world''s major areas of chemical research.