[Herbal cake-separated moxibustion at Baliao acupoints for erectile dysfunction with kidney deficiency and blood stasis: a randomized controlled trial].
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引用次数: 0
Abstract
Objective: To compare the clinical efficacy of herbal cake-separated moxibustion at Baliao acupoints combined with western medication versus western medication alone in treating erectile dysfunction (ED) with kidney deficiency and blood stasis.
Methods: A total of 108 ED patients were randomly divided into a combination group (54 cases, 2 cases dropped out) and a western medication group (54 cases, 1 case was eliminated, 2 cases dropped out). The western medication group received oral tadalafil tablets 5 mg a time, once daily. The combination group received additional herbal cake-separated moxibustion at Baliao acupoints (Shangliao [BL31], Ciliao [BL32], Zhongliao [BL33], Xialiao [BL34]) twice weekly (administered on Tuesdays and Fridays). Both groups were treated for 4 weeks. The 5-question international index of erectile function (IIEF-5) score, erectile hardness assessment (EHS) score, TCM syndrome score, serum sex hormone levels (follicle-stimulating hormone [FSH], luteinizing hormone [LH], prolactin [PRL], testosterone [T]), penile hemodynamic parameters [peak systolic velocity (PSV) of penile cavernosal artery, end-diastolic velocity (EDV), resistance index (RI)] were compared before and after treatment between the two groups, and the safety and clinical efficacy were evaluated.
Results: After treatment, the IIEF-5 scores, EHS scores, serum T levels, PSV and RI of penile cavernosal artery were increased compared with those before treatment in the two groups (P<0.05). Except for RI, the combination group exhibited significantly higher improvements in the above indexes than those in the western medication group (P<0.05). After treatment, the TCM syndrome scores, the serum FSH, LH levels, and EDV in the two groups and the serum PRL level in the combination group were decreased compared with those before treatment (P<0.05), while the above indexes in the combination group were lower than those in the western medication group (P<0.05). The total effective rate of the combination group was 88.5% (46/52), which was superior to 72.5% (37/51) in the western medication group (P<0.05). No significant adverse reactions occurred in either group.
Conclusion: Herbal cake-separated moxibustion at Baliao acupoints combined with western medicine can regulate sex hormone levels, improve penile blood supply, enhance erectile function and hardness, and is superior to western medication alone, with no observed adverse reactions.
期刊介绍：
Chinese Acupuncture and Moxibustion (founded in 1981, monthly) is an authoritative academic journal of acupuncture and moxibustion under the supervision of China Association for Science and Technology and co-sponsored by Chinese Acupuncture and Moxibustion Society and Institute of Acupuncture and Moxibustion of China Academy of Traditional Chinese Medicine. It is recognised as a core journal of Chinese science and technology, a core journal of Chinese language, and is included in the core journals of China Science Citation Database, as well as being included in MEDLINE and other international well-known medical index databases. The journal adheres to the tenet of ‘improving, taking into account the popularity, colourful and realistic’, and provides valuable learning and communication opportunities for the majority of acupuncture and moxibustion clinical and scientific research workers, and plays an important role in the domestic and international publicity and promotion of acupuncture and moxibustion disciplines.
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