Revision Total Hip Arthroplasty in Juvenile Idiopathic Arthritis: Survivorship After a Mean Follow-up of 11 Years.

IF 3.8 2区 医学 Q1 ORTHOPEDICS
Puthi Tantikosol, Katherine Hwang, Nicole Alexandriadria Segovia, Stuart B Goodman
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引用次数: 0

Abstract

Background: Juvenile idiopathic arthritis (JIA) is a chronic inflammatory condition that often affects the hip joints during childhood. Due to the high incidence of failure of initial total hip arthroplasty (THA) performed years earlier for JIA, revision surgeries are frequently necessary and particularly challenging. This study evaluated the outcomes of these complex revision procedures after an average follow-up of 11 years.

Methods: A retrospective review of 24 patients (34 hips) who had JIA undergoing revision THA between January 1999 and December 2023 was conducted. The mean age of the cohort was 40 years (range, 17 to 61), with an equal number of men and women patients. All surgeries were performed by a single surgeon. Data sources included clinical records and surgical reports. Univariate analyses were performed using Mann-Whitney tests for continuous variables and Chi-square/Fisher's exact tests for categorical variables. Kaplan-Meier survival curves were generated to estimate reoperation-free survival.

Results: The Kaplan-Meier survival analysis showed reoperation-free survival rates of 54% at five years and 36% at 10 years. The 95% CI (confidence intervals) for these estimates were 31 to 93% and 17 to 80%, respectively. Univariate analyses revealed a significant association between complications and length of hospital stay (hazard ratio [HR]: 0.15; 95% CI: 0.03 to 0.72; P = 0.018). A total of 41.2% of patients experienced complications such as infection, nerve palsy, and dislocation.

Conclusions: Revision THA in patients who had JIA is associated with a high complication rate and reduced reoperation-free survival. Early identification of risk factors, meticulous surgical planning, and comprehensive postoperative care are critical to improving long-term outcomes.

青少年特发性关节炎的翻修全髋关节置换术:平均随访11年后的生存率。
背景:青少年特发性关节炎(JIA)是一种慢性炎症,常在儿童时期影响髋关节。由于多年前对JIA进行的首次全髋关节置换术(THA)失败率高,翻修手术经常是必要的,尤其具有挑战性。在平均随访11年后,本研究评估了这些复杂翻修手术的结果。方法:对1999年1月至2023年12月间24例(34髋)JIA行翻修THA的患者进行回顾性分析。该队列的平均年龄为40岁(范围17至61岁),男女患者人数相等。所有手术均由一名外科医生完成。数据来源包括临床记录和手术报告。对连续变量采用Mann-Whitney检验,对分类变量采用Chi-square/Fisher精确检验进行单因素分析。生成Kaplan-Meier生存曲线来估计无再手术生存期。结果:Kaplan-Meier生存分析显示5年无再手术生存率为54%,10年无再手术生存率为36%。这些估计的95% CI(置信区间)分别为31 ~ 93%和17 ~ 80%。单因素分析显示,并发症与住院时间之间存在显著关联(风险比[HR]: 0.15; 95% CI: 0.03 ~ 0.72; P = 0.018)。41.2%的患者出现感染、神经麻痹、脱位等并发症。结论:JIA患者翻修THA与高并发症发生率和降低无再手术生存率相关。早期识别危险因素,精心的手术计划和全面的术后护理是改善长期预后的关键。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Arthroplasty
Journal of Arthroplasty 医学-整形外科
CiteScore
7.00
自引率
20.00%
发文量
734
审稿时长
48 days
期刊介绍: The Journal of Arthroplasty brings together the clinical and scientific foundations for joint replacement. This peer-reviewed journal publishes original research and manuscripts of the highest quality from all areas relating to joint replacement or the treatment of its complications, including those dealing with clinical series and experience, prosthetic design, biomechanics, biomaterials, metallurgy, biologic response to arthroplasty materials in vivo and in vitro.
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