Comparative Analysis of Maxillary Sinus Volume in Patients With Cleft Lip and Palate Versus Class III Malocclusion Patients Using CBCT.

IF 1.7 3区医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE

Orthodontics & Craniofacial Research Pub Date : 2025-10-10 DOI:10.1111/ocr.70041

Sara Eslami, Anand Marya, Babak Sayahpour, Sarah Bühling, Stefan Kopp, Hanieh Mahmoudi, Ahmadreza Talaeipour, Ari Harsoputranto, Abdolreza Jamilian

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引用次数: 0

Abstract

Objectives: This study compared maxillary sinus volume (MSV) in patients with unilateral non-syndromic cleft lip and palate (CLP) to a skeletally matched control group with a skeletal class III pattern (group CTR) using cone-beam computed tomography (CBCT) images.

Materials/methods: Ninety CBCT images were evaluated, including 45 patients with unilateral CLP (group CLP, mean age 24.3 ± 6.1) and 45 patients with Class III malocclusion (group CTR, mean age 25.3 ± 5.9). Both groups were skeletally matched based on SNA, SNB, ANB, GoGn-SN angles and Wits appraisal values. MSV was measured using ITK-SNAP software. The Kolmogorov-Smirnov test confirmed normal data distribution. Intergroup comparisons of average MSV, MSV stratified per side, cephalometric parameters and gender differences were performed using Student's t-test. Intragroup comparisons (cleft vs. non-cleft side, right vs. left side) were conducted using a paired t-test. Statistical significance was set at p < 0.05.

Results: No statistically significant differences in average MSV were found between the CLP group (7589.74 ± 4060.23 mm³) and the CTR group (7901.90 ± 3667.69 mm³) (p = 0.59). However, within the CLP group, the MSV on the cleft side (6870.53 ± 3695.29 mm³) was significantly smaller than on the non-cleft side (8308.96 ± 4316.53 mm³) (p < 0.05). No significant gender differences regarding MSV values were found (p > 0.05).

Conclusions: Unilateral cleft lip and palate resulted in a significantly smaller MSV on the cleft side in CLP patients. However, the average MSV of CLP patients was not significantly reduced compared to non-cleft patients with a skeletal Class III pattern.

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用CBCT对唇腭裂与ⅲ类错颌患者上颌窦容积的比较分析。

目的：本研究使用锥束计算机断层扫描（CBCT）图像比较单侧非综合征性唇腭裂（CLP）患者的上颌窦体积（MSV）与骨骼匹配的对照组（CTR组）骨骼III类模式。材料/方法：选取45例单侧CLP患者（CLP组，平均年龄24.3±6.1岁）和45例III类错颌合患者（CTR组，平均年龄25.3±5.9岁）的90张CBCT图像进行评价。根据SNA、SNB、ANB、GoGn-SN角度和Wits评价值对两组进行骨骼匹配。采用ITK-SNAP软件测量MSV。Kolmogorov-Smirnov检验证实数据呈正态分布。组间比较平均MSV、每侧分层MSV、头侧测量参数和性别差异采用学生t检验。组内比较（裂侧与非裂侧，右侧与左侧）采用配对t检验进行。结果：CLP组（7589.74±4060.23 mm3）与CTR组（7901.90±3667.69 mm3）的平均MSV差异无统计学意义（p = 0.59）。CLP组唇裂侧的MSV（6870.53±3695.29 mm3）明显小于非唇裂侧的MSV(8308.96±4316.53 mm3) （p 0.05）。结论：单侧唇腭裂导致CLP患者唇裂侧的MSV明显减小。然而，CLP患者的平均MSV与骨骼类型为III的非腭裂患者相比并没有显著降低。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Orthodontics & Craniofacial Research 医学-牙科与口腔外科

CiteScore

5.30

自引率

3.20%

发文量

审稿时长

>12 weeks

期刊介绍： Orthodontics & Craniofacial Research - Genes, Growth and Development is published to serve its readers as an international forum for the presentation and critical discussion of issues pertinent to the advancement of the specialty of orthodontics and the evidence-based knowledge of craniofacial growth and development. This forum is based on scientifically supported information, but also includes minority and conflicting opinions. The objective of the journal is to facilitate effective communication between the research community and practicing clinicians. Original papers of high scientific quality that report the findings of clinical trials, clinical epidemiology, and novel therapeutic or diagnostic approaches are appropriate submissions. Similarly, we welcome papers in genetics, developmental biology, syndromology, surgery, speech and hearing, and other biomedical disciplines related to clinical orthodontics and normal and abnormal craniofacial growth and development. In addition to original and basic research, the journal publishes concise reviews, case reports of substantial value, invited essays, letters, and announcements. The journal is published quarterly. The review of submitted papers will be coordinated by the editor and members of the editorial board. It is policy to review manuscripts within 3 to 4 weeks of receipt and to publish within 3 to 6 months of acceptance.