[Expression of Concern] Combination of the FGFR4 inhibitor PD173074 and 5‑fluorouracil reduces proliferation and promotes apoptosis in gastric cancer.

IF 3.9 3区 医学 Q2 ONCOLOGY
Oncology reports Pub Date : 2025-12-01 Epub Date: 2025-10-10 DOI:10.3892/or.2025.9004
Yan-Wei Ye, Shuang Hu, Ying-Qiang Shi, Xie-Fu Zhang, Ye Zhou, Chun-Lin Zhao, Guo-Jun Wang, Jian-Guo Wen, Hong Zong
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引用次数: 0

Abstract

Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that, for the western blot data shown in Figs. 1E and 4, the FGFR blots and control GAPDH blots were both strikingly similar in these figures, suggesting that the same data had been included in these, even though the results from differently performed experiments were intended to have been portrayed. The authors were contacted by the Editorial Office to offer an explanation for these apparent anomalies in the presentation of the data in this paper; however, up to this time, no response from them has been forthcoming. Owing to the fact that the Editorial Office has been made aware of potential issues surrounding the scientific integrity of this paper, we are issuing an Expression of Concern to notify readers of this potential problem while the Editorial Office continues to investigate this matter further.  [Oncology Reports 30: 2777‑2784, 2013; DOI: 10.3892/or.2013.2796].

[关注表达]FGFR4抑制剂PD173074与5‑氟尿嘧啶联合使用可减少胃癌细胞增殖,促进细胞凋亡。
在本文发表后,一位关心的读者提请编辑注意,对于图1E和图4所示的western blot数据,FGFR印迹和对照GAPDH印迹在这些数据中都惊人地相似,这表明这些数据中包含了相同的数据,尽管不同实验的结果是有意被描绘出来的。编辑部联系了作者,要求对本文数据呈现中的这些明显异常进行解释;然而,到目前为止,他们还没有任何回应。由于编辑部已经意识到围绕本文科学完整性的潜在问题,在编辑部继续进一步调查此事的同时,我们发出一份关注表达,通知读者这一潜在问题。肿瘤学报告30:2777‑2784,2013;DOI: 10.3892 / or.2013.2796]。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Oncology reports
Oncology reports 医学-肿瘤学
CiteScore
8.50
自引率
2.40%
发文量
187
审稿时长
3 months
期刊介绍: Oncology Reports is a monthly, peer-reviewed journal devoted to the publication of high quality original studies and reviews concerning a broad and comprehensive view of fundamental and applied research in oncology, focusing on carcinogenesis, metastasis and epidemiology.
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