A survey of PCF-based sensors for various disease detection applications

IF 2.7 3区计算机科学 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC

Optical Fiber Technology Pub Date : 2025-10-10 DOI:10.1016/j.yofte.2025.104439

Sreevani Alluru , Siva Prasad Valluri

{"title":"A survey of PCF-based sensors for various disease detection applications","authors":"Sreevani Alluru , Siva Prasad Valluri","doi":"10.1016/j.yofte.2025.104439","DOIUrl":null,"url":null,"abstract":"<div><div>Photonic crystal fibers (PCFs) have emerged as transformative tools for biomedical monitoring, offering exceptional sensitivity and versatility. This review examines the first comprehensive survey of PCF-based sensors designed explicitly for disease detection, including cancer, malaria, Alzheimer’s disease, COVID-19, brain tumors, and physiological parameters. Key design parameters, including core geometry, material selection, and functional coatings, are analyzed to elucidate their impact on performance metrics such as refractive index sensitivity, detection limit, and spectral response. Additionally, this review highlights the computation of essential characteristics namely confinement loss, relative sensitivity, wavelength sensitivity, and amplitude sensitivity, providing a comprehensive perspective on their capabilities and applications. This review also addresses the limitations, problems, and advantages of the various PCF structures. Finally, we discuss fabrication challenges and outline future opportunities, including Artificial Intelligence (AI) integration and multi-disease biosensing.</div></div>","PeriodicalId":19663,"journal":{"name":"Optical Fiber Technology","volume":"95 ","pages":"Article 104439"},"PeriodicalIF":2.7000,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Optical Fiber Technology","FirstCategoryId":"94","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1068520025003141","RegionNum":3,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ENGINEERING, ELECTRICAL & ELECTRONIC","Score":null,"Total":0}

引用次数: 0

Abstract

Photonic crystal fibers (PCFs) have emerged as transformative tools for biomedical monitoring, offering exceptional sensitivity and versatility. This review examines the first comprehensive survey of PCF-based sensors designed explicitly for disease detection, including cancer, malaria, Alzheimer’s disease, COVID-19, brain tumors, and physiological parameters. Key design parameters, including core geometry, material selection, and functional coatings, are analyzed to elucidate their impact on performance metrics such as refractive index sensitivity, detection limit, and spectral response. Additionally, this review highlights the computation of essential characteristics namely confinement loss, relative sensitivity, wavelength sensitivity, and amplitude sensitivity, providing a comprehensive perspective on their capabilities and applications. This review also addresses the limitations, problems, and advantages of the various PCF structures. Finally, we discuss fabrication challenges and outline future opportunities, including Artificial Intelligence (AI) integration and multi-disease biosensing.

查看原文本刊更多论文

基于pcf的各种疾病检测传感器的调查

光子晶体光纤（pcf）已成为生物医学监测的变革性工具，具有卓越的灵敏度和多功能性。本文综述了首次全面调查明确设计用于疾病检测的基于pcf的传感器，包括癌症、疟疾、阿尔茨海默病、COVID-19、脑肿瘤和生理参数。分析了关键设计参数，包括核心几何形状、材料选择和功能涂层，以阐明它们对折射率灵敏度、检测极限和光谱响应等性能指标的影响。此外，本文还重点介绍了约束损耗、相对灵敏度、波长灵敏度和幅度灵敏度等基本特性的计算，并对它们的能力和应用进行了全面的介绍。本文还讨论了各种PCF结构的局限性、问题和优点。最后，我们讨论了制造挑战并概述了未来的机遇，包括人工智能（AI）集成和多疾病生物传感。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Optical Fiber Technology 工程技术-电信学

CiteScore

4.80

自引率

11.10%

发文量

327

审稿时长

63 days

期刊介绍： Innovations in optical fiber technology are revolutionizing world communications. Newly developed fiber amplifiers allow for direct transmission of high-speed signals over transcontinental distances without the need for electronic regeneration. Optical fibers find new applications in data processing. The impact of fiber materials, devices, and systems on communications in the coming decades will create an abundance of primary literature and the need for up-to-date reviews. Optical Fiber Technology: Materials, Devices, and Systems is a new cutting-edge journal designed to fill a need in this rapidly evolving field for speedy publication of regular length papers. Both theoretical and experimental papers on fiber materials, devices, and system performance evaluation and measurements are eligible, with emphasis on practical applications.